ING1 and DMAP1

Data Source:
HPRD (in vitro, in vivo)

		ING1	DMAP1
Description		inhibitor of growth family member 1	DNA methyltransferase 1 associated protein 1
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GO Annotations	Cellular Component	Nucleus	Swr1 Complex Nucleus Nucleoplasm Replication Fork Cytoplasm Cytosol NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Methylated Histone Binding Metal Ion Binding	RNA Polymerase II Repressing Transcription Factor Binding Transcription Corepressor Activity Protein Binding
	Biological Process	Cell Cycle Negative Regulation Of Cell Population Proliferation Regulation Of Cell Death Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II DNA Repair DNA Methylation Regulation Of Growth Positive Regulation Of Protein Import Into Nucleus Histone Exchange Histone H4 Acetylation Histone H2A Acetylation Response To Ethanol Negative Regulation Of Transcription, DNA-templated
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Erosive tooth wear (severe vs non-severe) ( 29898447)	Metabolite levels ( 23823483)
Interacting Genes		29 interacting genes: BRMS1 BRMS1L COPS2 CYTOR DMAP1 EP300 ESR1 EXOC4 H3C14 HDAC1 HDAC2 KAT2B MRGBP NQO1 PCNA RBBP4 RBBP7 RBP1 SAP30 SFN SIN3A TP53 UBC YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	38 interacting genes: ARFIP2 BFSP2 C1orf216 CCHCR1 CDCA7L DAXX DNMT1 EXOC8 GAS8 GINS4 HDAC2 HSF2BP HSPB1 ING1 KRT75 LMNB1 LRSAM1 MIS18A MNAT1 MORF4L1 MRGBP NAP1L2 PFDN1 PIBF1 RGS6 SAAL1 SBK3 SUOX TCEANC TCHP TLK2 TOMM34 TRIM21 TSG101 TSGA10IP TXLNA TXLNB URI1
Entrez ID		3621	55929
HPRD ID		03337	05465
Ensembl ID		ENSG00000153487	ENSG00000178028
Uniprot IDs		A0A0C4DFW2 Q9UK53	Q9NPF5
PDB IDs		2QIC	3HM5 4IEJ
Enriched GO Terms of Interacting Partners?
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