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ING1 and RBBP4
Data Source:
HPRD
(in vivo)
ING1
RBBP4
Description
inhibitor of growth family member 1
RB binding protein 4, chromatin remodeling factor
Image
GO Annotations
Cellular Component
Nucleus
Chromatin
Nucleus
Nucleoplasm
Cytosol
Sin3 Complex
NuRD Complex
NURF Complex
Protein-containing Complex
CAF-1 Complex
ESC/E(Z) Complex
Molecular Function
Protein Binding
Methylated Histone Binding
Metal Ion Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Protein Binding
DNA-dependent ATPase Activity
Nucleosomal DNA Binding
Histone Binding
Histone Deacetylase Binding
Biological Process
Cell Cycle
Negative Regulation Of Cell Population Proliferation
Regulation Of Cell Death
Negative Regulation Of Cell Growth
Positive Regulation Of Transcription, DNA-templated
DNA Replication
DNA Replication-dependent Nucleosome Assembly
DNA Replication-independent Nucleosome Assembly
Chromatin Remodeling
Cell Cycle
Negative Regulation Of Cell Population Proliferation
Chromatin Assembly
CENP-A Containing Nucleosome Assembly
ATP-dependent Chromatin Remodeling
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Cell Cycle
Response To Growth Hormone
Negative Regulation Of G0 To G1 Transition
Regulation Of Signal Transduction By P53 Class Mediator
Pathways
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
Polo-like kinase mediated events
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
HDACs deacetylate histones
PKMTs methylate histone lysines
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Deposition of new CENPA-containing nucleosomes at the centromere
Regulation of TP53 Activity through Acetylation
Cyclin E associated events during G1/S transition
G1/S-Specific Transcription
Cyclin A:Cdk2-associated events at S phase entry
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
HCMV Early Events
Potential therapeutics for SARS
Drugs
Diseases
GWAS
Blood protein levels (
30072576
)
Erosive tooth wear (severe vs non-severe) (
29898447
)
Interacting Genes
29 interacting genes:
BRMS1
BRMS1L
COPS2
CYTOR
DMAP1
EP300
ESR1
EXOC4
H3C14
HDAC1
HDAC2
KAT2B
MRGBP
NQO1
PCNA
RBBP4
RBBP7
RBP1
SAP30
SFN
SIN3A
TP53
UBC
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
64 interacting genes:
AEBP2
ANXA7
ARMC12
BCL11A
BCL11B
BRCA1
BRMS1
BRMS1L
CDKN1A
CHAF1B
CREB1
CREBBP
CYTOR
DHX30
ERCC6
ESR1
FOXK2
H1-1
H2AC20
H3-4
H3C1
H3C14
H4-16
H4C14
HAT1
HDAC1
HDAC2
HDAC3
HDAC4
HMOX2
ING1
KPNA3
KPNA5
LIN37
LIN52
LIN9
LMNA
MBD2
MBD3
MBD3L2
MTA1
MTA2
MYBL2
NR2E3
PRDM16
RB1
RBBP7
RBP1
RPN1
RPN2
RYBP
SALL4
SAP30
SIN3A
SMN1
SP1
SP3
SPEN
STAT5B
SUMO2
SUV39H1
TK1
TSSK3
XRCC6
Entrez ID
3621
5928
HPRD ID
03337
04232
Ensembl ID
ENSG00000153487
ENSG00000162521
Uniprot IDs
A0A0C4DFW2
Q9UK53
Q09028
PDB IDs
2QIC
2XU7
3GFC
4PBY
4PBZ
4PC0
4R7A
5FXY
5VTB
5WAI
5WAK
5XWR
5XXQ
5Y1U
6BW3
6BW4
6C23
6C24
6G16
6NQ3
6ZRC
Enriched GO Terms of Interacting Partners
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