RALGDS and RIT1

Data Source:
HPRD (two hybrid)

		RALGDS	RIT1
Description		ral guanine nucleotide dissociation stimulator	Ras like without CAAX 1
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GO Annotations	Cellular Component	Nucleus Cytosol Brush Border	Plasma Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Regulator Activity	GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Ras Protein Signal Transduction Regulation Of Catalytic Activity	Signal Transduction Ras Protein Signal Transduction
Pathways		p38MAPK events p38MAPK events RAF/MAP kinase cascade	Signalling to p38 via RIT and RIN
Drugs
Diseases
GWAS		Blood protein levels in cardiovascular risk ( 28369058)	Birth weight ( 31043758) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		26 interacting genes: AFDN ARRB1 ARRB2 CD68 CNKSR1 CYSRT1 HOXA1 HRAS KRAS KRTAP10-8 LRPAP1 MAPK3 MRAS NF2 PDPK1 RAP1A RAP1B RAP1GAP RAP2A RAP2B RAPGEF2 RIN1 RIT1 RIT2 RRAS RRAS2	17 interacting genes: AFDN AP2A1 CUL3 IFRD1 KLHL12 LRIF1 LRRK2 LZTR1 PTN RALGDS RGL1 RGL3 RLF SMAD2 SMAD3 SMURF1 SRPK2
Entrez ID		5900	6016
HPRD ID		03371	10195
Ensembl ID		ENSG00000160271	ENSG00000143622
Uniprot IDs		Q12967 Q8N4Y1	Q92963
PDB IDs		1RAX 2B3A 2RGF 3KH0	4KLZ
Enriched GO Terms of Interacting Partners?
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