RIT1 and IFRD1

Data Source:
HPRD (two hybrid)

		RIT1	IFRD1
Description		Ras like without CAAX 1	interferon related developmental regulator 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Nucleus
	Molecular Function	GTPase Activity Protein Binding Calmodulin Binding GTP Binding GDP Binding
	Biological Process	Signal Transduction Ras Protein Signal Transduction	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Myoblast Fate Determination
Pathways		Signalling to p38 via RIT and RIN
Drugs
Diseases
GWAS		Birth weight ( 31043758) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Immature fraction of reticulocytes ( 32888494) Inflammatory bowel disease ( 28067908 23128233) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Amyotrophic lateral sclerosis (age of onset) ( 22959728) Dental caries (decayed, missing and filled teeth) ( 31533690) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Mortality in heart failure ( 20400778) Osteoarthritis (hip) ( 23989986) Refractive error ( 32231278)
Interacting Genes		17 interacting genes: AFDN AP2A1 CUL3 IFRD1 KLHL12 LRIF1 LRRK2 LZTR1 PTN RALGDS RGL1 RGL3 RLF SMAD2 SMAD3 SMURF1 SRPK2	6 interacting genes: CSNK2A1 HDAC2 HDAC4 KLHL41 MYOD1 RIT1
Entrez ID		6016	3475
HPRD ID		10195	04612
Ensembl ID		ENSG00000143622	ENSG00000006652
Uniprot IDs		Q92963	A4D0U1 O00458
PDB IDs		4KLZ
Enriched GO Terms of Interacting Partners?
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