Description |
Raf-1 proto-oncogene, serine/threonine kinase |
EGF containing fibulin extracellular matrix protein 1 |
Image |
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No pdb structure |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Asthma ( 32296059)
- Cardiac hypertrophy ( 21348951)
- Carotid intima media thickness x smoking interaction ( 32117412)
- Cholesterol, total ( 24097068 20686565)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- HDL cholesterol levels ( 32203549)
- Total cholesterol levels ( 28334899)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
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Interacting Genes |
160 interacting genes:
ABCB5
ADCY6
AGTR1
AKT1
AR
ARNT
ARRB2
BAD
BAG1
BCL2
BCL2L1
BCL6
BECN1
BIRC2
BIRC3
BRAF
CASZ1
CBLC
CCND2
CCT3
CD44
CDC25A
CDC37
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
CFLAR
CNKSR1
COPS3
COPS7A
CPS1
DCAF8
DMPK
EFEMP1
EGFR
EPHA2
ERBB2
ERBIN
FGFR4
FYCO1
FYN
GLIS2
GNB2
GNG4
GRB10
GRM1
HERC1
HGF
HRAS
HSP90AA1
HSPA4
HSPA8
IL2RB
INSR
INTS10
JAK1
JAK2
KEAP1
KRAS
KRT18
KRT8
KSR1
KSR2
LATS2
LCK
LOX
LRPAP1
MAP2K1
MAP2K2
MAP2K3
MAP2K5
MAP2K6
MAP3K1
MAP3K5
MAPK1
MAPK3
MAPK7
MAPK8
MAPK8IP3
MBP
MET
MRAS
MRC2
MYBPC1
MYC
NEDD4
NF1
NF2
NPLOC4
NR3C1
NRAS
NUDT14
OIP5
PACSIN3
PAK1
PAK2
PAK3
PBK
PDGFRA
PDGFRB
PDLIM2
PEBP1
PEBP4
PEX5L
PHB
PHKA2
PIN1
PKM
PPP1CC
PPP2CB
PRKAA1
PRKACA
PRKAR1A
PRKCA
PRKCD
PRKCE
PRKCZ
PRKG1
PRPF6
PURA
RANBP9
RAP1A
RAP2A
RASD2
RASSF1
RB1
RBBP8
RBL2
RFXANK
RHEB
RRAS
RRAS2
RSU1
SHOC2
SPRY2
SPRY4
SRC
STK26
STK3
STUB1
TBXA2R
TEAD2
TERT
TIMM50
TMEM70
TSC22D3
UBE2D2
UBE2L3
VAV1
VDAC1
XIAP
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
YY1
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42 interacting genes:
ANAPC11
ARAF
ATN1
ATXN7
BAG4
BAG5
BAG6
CACNA1A
CLPP
CRYBA4
CYSRT1
DDIAS
ERRFI1
FAM110A
GFI1B
HOXA1
HSD3B7
IGFBP6
KHDRBS1
KRTAP19-2
KRTAP21-2
KRTAP6-1
LCE1C
LCE2C
LCE3A
LCE3D
MEOX2
MKRN3
MSRB3
NOS3
NR4A3
RAF1
RERE
RIC8A
SGTA
SLPI
SOCS6
TIMP3
TNIP1
TRAF2
TXNDC5
UBQLN2
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Entrez ID |
5894 |
2202 |
HPRD ID |
01265 |
03331 |
Ensembl ID |
ENSG00000132155
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ENSG00000115380
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Uniprot IDs |
A0A0S2Z4L5
L7RRS6
P04049
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A0A0S2Z3V1
A0A0S2Z4F1
B2R6M6
Q12805
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PDB IDs |
1C1Y
1FAQ
1FAR
1GUA
1RFA
3CU8
3IQJ
3IQU
3IQV
3KUC
3KUD
3NKX
3O8I
3OMV
4FJ3
4G0N
4G3X
4IEA
4IHL
6NTC
6NTD
6PTS
6PTW
7JHP
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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