Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
SNX6 and ACVR2B
Data Source:
HPRD
(in vitro, in vivo)
SNX6
ACVR2B
Description
sorting nexin 6
activin A receptor type 2B
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Endosome
Cytosol
Retromer Complex
Retromer, Tubulation Complex
Early Endosome Membrane
Tubular Endosome
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Protein-containing Complex
Receptor Complex
Activin Receptor Complex
Molecular Function
Protein Binding
Dynactin Binding
Phosphatidylinositol Binding
Protein Homodimerization Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Activin Receptor Activity, Type II
Activin-activated Receptor Activity
Growth Factor Binding
Metal Ion Binding
Activin Binding
Biological Process
Intracellular Protein Transport
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Regulation Of Macroautophagy
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Retrograde Transport, Endosome To Golgi
Negative Regulation Of Neuron Apoptotic Process
Negative Regulation Of Transcription, DNA-templated
Regulation Of Histamine Secretion By Mast Cell
Cellular Response To Amyloid-beta
Negative Regulation Of Transcription By RNA Polymerase II
Lymphangiogenesis
Blood Vessel Remodeling
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Signal Transduction
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Anterior/posterior Pattern Specification
Positive Regulation Of Bone Mineralization
BMP Signaling Pathway
Activin Receptor Signaling Pathway
Positive Regulation Of Activin Receptor Signaling Pathway
Positive Regulation Of Osteoblast Differentiation
Lymphatic Endothelial Cell Differentiation
Artery Development
Venous Blood Vessel Development
Retina Vasculature Development In Camera-type Eye
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Cold-induced Thermogenesis
Pathways
Signaling by NODAL
Regulation of signaling by NODAL
Signaling by Activin
Signaling by Activin
Signaling by BMP
Drugs
Diseases
Heterotaxy; Situs ambiguus
GWAS
Atrial fibrillation (
29892015
)
Celiac disease (
23936387
)
Diastolic blood pressure (
30224653
)
Normal facial asymmetry (angle of surface orientation score) (
30631343
)
Bitter beverage consumption (
31046077
)
Body size at age 10 (
32376654
)
Estimated glomerular filtration rate (
31152163
31015462
)
P wave duration (
24850809
)
Interacting Genes
25 interacting genes:
ACVR2B
ACVRL1
BMPR1B
BRCA1
BRMS1
CALM1
COIL
CSNK2A2
DISC1
EGFR
ESR1
INSR
LEPR
NDEL1
OPTN
PDGFRA
PIM1
SNX1
SNX2
SNX4
TEX11
TGFBR1
TGFBR2
TNIK
TPT1
21 interacting genes:
ACVR1B
BMP10
BMP2
BMP7
ERBIN
FBXO7
GDF11
GDF2
GDF5
IGSF1
INHBA
INHBB
INHBC
MSTN
NODAL
SNX1
SNX2
SNX6
SYNJ2BP
TDGF1
TGFBRAP1
Entrez ID
58533
93
HPRD ID
12086
04106
Ensembl ID
ENSG00000129515
ENSG00000114739
Uniprot IDs
A0A0A0MRI2
Q9UNH7
Q13705
PDB IDs
2H62
2QLU
4FAO
5NGV
5NHR
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?