SNX6 and OPTN

  • Data Source:
  • BioGRID (two hybrid, imaging technique)

SNX6

OPTN

Description sorting nexin 6 optineurin
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Atrial fibrillation ( 29892015)
  • Celiac disease ( 23936387)
  • Diastolic blood pressure ( 30224653)
  • Normal facial asymmetry (angle of surface orientation score) ( 30631343)
Interacting Genes 25 interacting genes: ACVR2B ACVRL1 BMPR1B BRCA1 BRMS1 CALM1 COIL CSNK2A2 DISC1 EGFR ESR1 INSR LEPR NDEL1 OPTN PDGFRA PIM1 SNX1 SNX2 SNX4 TEX11 TGFBR1 TGFBR2 TNIK TPT1 69 interacting genes: AIMP1 ARRDC3 ATG16L1 ATG5 CALM1 CCDC13 CDC23 CLTC CMYA5 DAZAP2 DYSF DZIP1 FAM189A2 FLII FOS FTH1 GABARAP GABARAPL1 GABARAPL2 GNAS GRM1 GTF3A HACE1 HSF2BP HSPB1 HTT IRAK1 KANSL1L LITAF LNX2 MAP1LC3A MAP1LC3C MPP1 MYH3 MYO6 PIAS4 PICK1 POU6F2 RAB11A RAB11B RAB12 RAB14 RAB25 RAB8A RBM12 RFFL RNF11 RNF216 SDCBP SLF2 SNX6 TBC1D15 TBC1D17 TNIP1 UBB UBC UQCRQ USP2 VCP WASHC3 WIPI2 ZNF17 ZNF181 ZNF302 ZNF329 ZNF398 ZNF426 ZNF670 ZNF711
Entrez ID 58533 10133
HPRD ID 12086 03891
Ensembl ID ENSG00000129515 ENSG00000123240
Uniprot IDs A0A0A0MRI2 Q9UNH7 Q96CV9
PDB IDs 2LO4 2LUE 3VTV 3VTW 5AAZ 5B83 5EOA 5EOF
Enriched GO Terms of Interacting Partners?
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