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MYOZ1 and PLEKHG4
Data Source:
BioGRID
(two hybrid)
MYOZ1
PLEKHG4
Description
myozenin 1
pleckstrin homology and RhoGEF domain containing G4
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Actin Cytoskeleton
Z Disc
Pseudopodium
Molecular Function
Actin Binding
Protein Serine/threonine Phosphatase Inhibitor Activity
Protein Binding
Telethonin Binding
FATZ Binding
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Skeletal Muscle Tissue Development
Myofibril Assembly
Negative Regulation Of Phosphoprotein Phosphatase Activity
Wound Healing
Negative Regulation Of Skeletal Muscle Tissue Regeneration
Skeletal Muscle Fiber Adaptation
Sarcomere Organization
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Atrial fibrillation (
30061737
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Blood protein levels (
29875488
28240269
)
Heel bone mineral density (
28869591
)
Refractive error (
32231278
)
Interacting Genes
40 interacting genes:
ACTN1
ACTN2
ACTN3
ACTN4
AKAP8L
APP
BAG4
BRCA1
CEACAM6
CEP76
CRX
EIF3F
EXOSC8
FLNA
FLNC
GOLGA6A
GRB2
KRT34
KRT36
KRTAP12-2
LDB3
LHX4
LZTS2
MAGEA11
PFDN5
PLEKHG4
PNKP
PNMA1
PRKAA2
TCAP
TRAF1
TRIM23
TRIM55
TRIM63
USHBP1
VAC14
VBP1
WASHC3
WWOX
YPEL3
65 interacting genes:
A1CF
ARHGEF5
ARMC7
BEX2
CCDC120
CCDC187
CDC42
CDKN2C
CHIC2
COIL
DCUN1D5
DPPA3
DTX2
DUSP13
FAM161A
FGD2
GATA3
GCM2
GSTZ1
HCK
HOXB9
HOXC8
KRT3
KRT75
MALSU1
MATR3
MDFI
METAP1
MSRB3
MTA1
MYEF2
MYOZ1
NATD1
OTX1
PFKFB1
PKP2
PPP1R32
PRPF18
PRPF31
PSMB1
RHOA
RIN1
SAXO1
SETD5
SH2D4A
SHISA6
SIX1
SMCP
SMG9
TBC1D22B
TBX18
TEKT3
TENT5D
TFAP2D
TFG
TRIM55
TRIM63
TSSK3
TTC23
USP2
VPS37C
ZCCHC14
ZNF148
ZNF319
ZNF648
Entrez ID
58529
25894
HPRD ID
05725
10890
Ensembl ID
ENSG00000177791
ENSG00000196155
Uniprot IDs
Q9NP98
A0A024R6X4
Q58EX7
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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