PLEKHG4 and TEKT3

Data Source:
BioGRID (two hybrid)

		PLEKHG4	TEKT3
Description		pleckstrin homology and RhoGEF domain containing G4	tektin 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Acrosomal Membrane Outer Acrosomal Membrane Nucleus Microtubule Cytoskeleton Sperm Flagellum Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Molecular_function Protein Binding
	Biological Process	Regulation Of Catalytic Activity	Flagellated Sperm Motility Cilium Assembly Cilium Movement Involved In Cell Motility Regulation Of Brood Size
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Heel bone mineral density ( 28869591) Refractive error ( 32231278)	Preterm birth (maternal effect) ( 28877031) Resting heart rate ( 27798624)
Interacting Genes		65 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	33 interacting genes: AJUBA ARID5A ASPG ATN1 CALCOCO2 CNOT2 DDI1 GORASP2 HNRNPH1 IKZF3 INSC KRT34 KRTAP15-1 KRTAP19-5 KRTAP26-1 KRTAP3-1 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 LMO2 METTL27 OIP5 PLAGL2 PLEKHG4 RAMAC RFX6 SPAG8 TEX45 TNS2 TRAF2 TRIB3 WWOX
Entrez ID		25894	64518
HPRD ID		10890	18173
Ensembl ID		ENSG00000196155	ENSG00000125409
Uniprot IDs		A0A024R6X4 Q58EX7	Q9BXF9
PDB IDs
Enriched GO Terms of Interacting Partners?
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