PLEKHG4 and DPPA3

Data Source:
BioGRID (two hybrid)

		PLEKHG4	DPPA3
Description		pleckstrin homology and RhoGEF domain containing G4	developmental pluripotency associated 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Female Pronucleus Male Pronucleus Nucleus Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Methylated Histone Binding
	Biological Process	Regulation Of Catalytic Activity	Chromatin Organization Protection Of DNA Demethylation Of Female Pronucleus Negative Regulation Of DNA Demethylation Regulation Of Genetic Imprinting
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Heel bone mineral density ( 28869591) Refractive error ( 32231278)	Borderline personality disorder ( 28632202) White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes		65 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	14 interacting genes: DEPDC5 DYNLL1 DYNLL2 HAUS7 IPO5 KRT27 KRT76 NUP62 PLEKHG4 SERTAD3 SYCE1L TFIP11 TRIB3 ZNF618
Entrez ID		25894	359787
HPRD ID		10890	16331
Ensembl ID		ENSG00000196155	ENSG00000187569
Uniprot IDs		A0A024R6X4 Q58EX7	Q6W0C5
PDB IDs
Enriched GO Terms of Interacting Partners?
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