ZNF250 and TNS2

Data Source:
BioGRID (two hybrid)

		ZNF250	TNS2
Description		zinc finger protein 250	tensin 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Plasma Membrane Focal Adhesion
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Protein Tyrosine Phosphatase Activity Protein Binding Kinase Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Kidney Development Negative Regulation Of Cell Population Proliferation Response To Muscle Activity Cellular Homeostasis Collagen Metabolic Process Multicellular Organism Growth Peptidyl-tyrosine Dephosphorylation Intracellular Signal Transduction Negative Regulation Of Insulin Receptor Signaling Pathway Multicellular Organismal Homeostasis
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		109 interacting genes: ANKRD50 APOBEC3C BEGAIN CARD10 CARD9 CBY2 CCDC102B CCDC125 CCDC130 CCDC136 CCDC6 CCDC85B CDCA7L CDR2 CDR2L CEP44 CEP63 DPPA2 DRC3 DVL2 FAM124A FAM161A FDXACB1 FHL5 GAS8 GMCL1 GMNN GNPTAB GOLGA2 GOLGA6L9 GRAP2 GRIPAP1 GUCD1 HEXIM2 HMBOX1 HOMEZ HOOK1 HOOK2 HSF2BP KASH5 KIFC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP4-12 LDOC1 LMO2 LZTS1 LZTS2 MAGOHB MEOX2 MID2 MTUS2 MYF5 NDEL1 NEXN NINL NXF1 PIBF1 PICK1 PLEKHF2 PRDM14 PRPF31 RUBCN RUNDC3A SPECC1L SPRED2 SSX2IP STX1A SYNE4 TFF1 TMCC2 TNK1 TNNT1 TNS2 TOP3B TRAF1 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB43 ZBTB6 ZBTB8A ZC4H2 ZCCHC13 ZCCHC7 ZFP1 ZNF165 ZNF175 ZNF202 ZNF330 ZNF345 ZNF460 ZNF473 ZNF547 ZNF57 ZNF572 ZNF639 ZNF648 ZNF668 ZNF768 ZNF792 ZNF837 ZRANB1	150 interacting genes: ADCK5 AMMECR1 AP1S2 AQP1 ARID5A ASB3 AXL BAHD1 BLZF1 BRCA1 C11orf87 C1orf94 CATSPER1 CCDC33 CNNM3 COX6B2 CPSF7 CRX CSNK1E CTSZ DCAF11 DCAF8 DDIT4L DLC1 DOK3 DZIP1 DZIP3 EGFR ENKD1 EPB41L4A EPDR1 EPS8L2 ERBB2 ERBB3 ERBB4 FABP7 FAM114A1 FAM228A FASLG FGF21 FGFR1 FOXO1 GATA1 GBA3 GFI1B HOXA1 HOXB9 HOXC8 HUWE1 ID2 IHO1 INO80B ITGB3 ITGB5 ITGB7 KCTD9 KIF1A KIT KPRP KRT76 KRTAP1-3 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP13-1 KRTAP13-2 KRTAP23-1 KRTAP3-1 KRTAP4-4 KRTAP6-3 LASP1 LPXN LUZP4 MET MGAT5B MPEG1 MT2A MTDH MYBPHL MYH7B MYPOP NBPF19 NMU NOTCH2NLA NT5C NUBP2 OBSL1 OTX1 PATZ1 PER1 PHF1 PIN1 PKP1 PLB1 PLK3 PLSCR3 POLR1H POLR3F PRR22 RAMAC RBAK RBPMS REEP6 REL RFT1 RNF6 SDCCAG8 SERTAD2 SH2B3 SHFL SOCS7 SORBS3 SPATA12 SPRY2 SPRY4 SUSD2 SUV39H1 TBC1D16 TCP10L TEKT3 TEKT5 TENT5A TENT5B TFAP2D TLE5 TM4SF19 TRIM8 TSC1 TWSG1 USP54 WAC WDFY3 ZCCHC14 ZIM2 ZNF134 ZNF205 ZNF250 ZNF417 ZNF497 ZNF575 ZNF586 ZNF587 ZNF648 ZNF655 ZNF688 ZNF837
Entrez ID		58500	23371
HPRD ID		15758	16256
Ensembl ID		ENSG00000196150	ENSG00000111077
Uniprot IDs		B3KNS9 P15622	A0A024RB48 Q63HR2
PDB IDs			2DKQ 2KNO 2L6K 2LOZ 3HQC
Enriched GO Terms of Interacting Partners?
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