ZNF250 and TRIM23

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		ZNF250	TRIM23
Description		zinc finger protein 250	tripartite motif containing 23
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Membrane Nucleus Cytoplasm Lysosomal Membrane Plasma Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Metal Ion Binding Sequence-specific Double-stranded DNA Binding	GTPase Activity Ubiquitin-protein Transferase Activity Protein Binding GTP Binding Enzyme Activator Activity Zinc Ion Binding GDP Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Intracellular Protein Transport Viral Process Vesicle-mediated Transport Protein Ubiquitination Innate Immune Response Regulation Of Catalytic Activity
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Logical memory (immediate recall) in normal cognition ( 29274321)	Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		109 interacting genes: ANKRD50 APOBEC3C BEGAIN CARD10 CARD9 CBY2 CCDC102B CCDC125 CCDC130 CCDC136 CCDC6 CCDC85B CDCA7L CDR2 CDR2L CEP44 CEP63 DPPA2 DRC3 DVL2 FAM124A FAM161A FDXACB1 FHL5 GAS8 GMCL1 GMNN GNPTAB GOLGA2 GOLGA6L9 GRAP2 GRIPAP1 GUCD1 HEXIM2 HMBOX1 HOMEZ HOOK1 HOOK2 HSF2BP KASH5 KIFC3 KRT31 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP4-12 LDOC1 LMO2 LZTS1 LZTS2 MAGOHB MEOX2 MID2 MTUS2 MYF5 NDEL1 NEXN NINL NXF1 PIBF1 PICK1 PLEKHF2 PRDM14 PRPF31 RUBCN RUNDC3A SPECC1L SPRED2 SSX2IP STX1A SYNE4 TFF1 TMCC2 TNK1 TNNT1 TNS2 TOP3B TRAF1 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB43 ZBTB6 ZBTB8A ZC4H2 ZCCHC13 ZCCHC7 ZFP1 ZNF165 ZNF175 ZNF202 ZNF330 ZNF345 ZNF460 ZNF473 ZNF547 ZNF57 ZNF572 ZNF639 ZNF648 ZNF668 ZNF768 ZNF792 ZNF837 ZRANB1	218 interacting genes: ACTN4 AKTIP ANKRD36BP1 ANKRD55 AP3M1 AQP1 ARFGAP1 ARHGEF3 ARNT2 ATPAF2 ATXN7 BAG1 BAZ2B BICRAL BRME1 C2CD6 C8orf33 CARD9 CBX8 CCDC13 CCDC146 CCDC25 CCDC33 CDC20B CDC73 CDR2 CFAP53 CHP1P2 COX5B CPNE7 CREB5 CSRP2 CWF19L2 CXCL14 CYTH1 CYTH2 DCX DEPP1 DMC1 DMRT3 DNAAF4 DOCK2 EAF2 EHHADH EIF3D ENKD1 EPN2 EXOC3-AS1 FAM110A FAM133A FAM193B FAM83A FAM90A1 FBF1 FHIT FLAD1 FXR2 GAD1 GATA2 GCC2-AS1 GEM GGA2 GGA3 GLIDR GMCL2 GPANK1 GPKOW HAPLN2 HAUS1 HGS HNRNPLL HOXB5 HSPB7 IL16 IQCE IQUB JOSD1 JRK KAT5 KIFC3 KLHL42 KRT6A KRT75 KRT76 LAGE3 LENG1 LGALS14 LGALS3 LGALS8 LINC00526 LINC01018 LMO2 LMO3 LNX1 MDM2 MKRN3 MLH1 MORN4 MRPL4 MRPL45 MSRB3 MTFR2 MYEF2 MYOM1 MYOZ1 NAB2 NEDD9 NEK6 NFU1 NOXA1 NTAQ1 NUDT21 NXT2 PDE4D PHF1 PIAS2 PIK3R2 PITX1 PKP4 PLEKHA2 POLI POLL POM121 PPIL2 PPP1R15B PPP1R18 PRPF18 PRPF31 PSMA1 PSMB1 RAD18 RAMAC RCAN3 RIBC1 RIBC2 RIN1 RNF126 RNF213 RNF32 RNF34 RNF6 RSRC2 RTP5 RUFY1 SCNM1 SF1 SH2D4A SIAH1 SIRPA SLC25A6 SMG9 SNAI1 SNAI2 SNRPB SNRPB2 SNW1 SORBS3 SPG21 STK19 SUMO1P1 TACO1 TASOR2 TBC1D22B TCEA2 TCEANC TEPSIN TEX33 TMSB4X TNFAIP3 TRAF1 TRAIP TRIM27 TRIM29 TRIM31 TRIM32 TRIM42 TRIM55 TRIM63 TROAP TSEN54 TSG101 TSHZ3 TXNDC5 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2I UBE2L3 UBE2N UBE2U UBE2W UBOX5 UBQLN1 USP2 USP20 USP21 UTP23 VGLL1 WDR25 ZBTB16 ZBTB4 ZC2HC1C ZFAND2A ZNF20 ZNF250 ZNF408 ZNF417 ZNF474 ZNF564 ZNF581 ZNF587 ZNF688 ZNF835
Entrez ID		58500	373
HPRD ID		15758	03449
Ensembl ID		ENSG00000196150	ENSG00000113595
Uniprot IDs		B3KNS9 P15622	P36406
PDB IDs			5VZV 5VZW
Enriched GO Terms of Interacting Partners?
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