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CBX8 and PLEKHF2
Data Source:
BioGRID
(two hybrid)
CBX8
PLEKHF2
Description
chromobox 8
pleckstrin homology and FYVE domain containing 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Endoplasmic Reticulum
Transport Vesicle
Early Endosome Membrane
Molecular Function
Single-stranded RNA Binding
Protein Binding
Methylated Histone Binding
Ubiquitin-protein Transferase Activator Activity
Protein Binding
Phosphatidylinositol Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Cell Population Proliferation
Histone Ubiquitination
Positive Regulation Of Collagen Biosynthetic Process
Positive Regulation Of DNA Repair
Regulation Of Catalytic Activity
Cellular Response To Hydrogen Peroxide
Protein Transport
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
General risk tolerance (MTAG) (
30643258
)
Plateletcrit (
32888494
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Smoking status (ever vs never smokers) (
30643258
)
Youthful appearance (self-reported) (
32339537
)
Radiation response (
20923822
)
Interacting Genes
87 interacting genes:
ABLIM3
BACH2
BANP
BMI1
CALCOCO2
CARD10
CARD9
CCDC136
CCDC57
CEP70
DVL3
EEF1G
FHL3
FSD2
FXR1
GIGYF1
GOLGA2
GOLGA6L9
GPRASP2
GRIPAP1
H3-4
HAP1
HMBOX1
HOMEZ
HOOK2
HSF2BP
IKZF1
JADE2
JAKMIP1
KANK2
KAT5
KAT7
KCTD9
KIFC3
KRT31
KRT34
KRT40
LSM2
LZTS2
MB21D2
MCC
MDFI
MID2
MLLT1
MLLT3
MTUS2
NAB2
PAXIP1
PCGF5
PHACTR1
PIBF1
PICK1
PIH1D2
PLEKHF2
PNMA1
PNMA2
POLR1C
PRDM6
PRKAR1B
RASSF3
RING1
RPGRIP1
SESTD1
SETDB1
SOX5
TAX1BP1
TEPSIN
TFCP2
TFIP11
TRAF2
TRIB3
TRIM23
TRIM27
TRIM54
TSC22D4
TSGA10
TTC23
UNC119
USH1G
USP11
USP7
VIM
ZBTB14
ZBTB8A
ZBTB9
ZNF185
ZRANB1
168 interacting genes:
ABCG4
ACY3
ADAP1
AIDA
AIMP2
ANO9
APP
APPL1
ARID4B
ARL14EP
ASPH
BARHL2
BCAS2
BCAS3
BEND7
BLOC1S6
BOD1
BRD7
BSCL2
C11orf45
C1orf35
C3
CAVIN2
CBX8
CCDC146
CCDC172
CCDC25
CCDC85B
CDC20B
CEP44
CERK
CGGBP1
CHCHD2
CHIC2
COX5B
CRYBA1
DAZAP2
DMRT3
DNAAF11
DOCK2
DOCK3
DPPA4
DRAP1
DTX2
DUSP4
DUT
EIF3C
EML2
EXOC7
FAH
FBXO28
FBXW5
FGF13
FHL3
FLNA
FRMD8
GAGE12G
GAGE2E
GEM
GFER
GLUL
GNMT
GPBP1
GPBP1L1
GRAMD4
GTPBP2
HEBP2
HSPB7
INO80
KCNAB3
KRTAP10-10
KRTAP5-4
L3MBTL3
LDOC1
MAGI2
MAP2K1
MAX
MBIP
MBP
MEAF6
MFAP1
MIDN
MPP4
MRI1
NDUFA5
NFIA
NONO
NPM2
NSD2
NUDT2
NUTM1
P2RX7
PACSIN1
PAK1IP1
PDK4
PIK3R3
PPCDC
PPP1R18
PRDM14
PRKAG1
PRKAR1A
PRPSAP1
PTPN3
PWWP2A
RAB28
RABAC1
RADX
RARA
RASGEF1B
RGS10
RGS8
RPAP2
RPE
RPRM
RPS21
RSPO2
RTN1
RTN3
RTN4
S100A1
S100A13
SAMD11
SCYL1
SEC14L4
SEPTIN2
SEPTIN5
SEPTIN6
SETBP1
SFN
SNRNP35
SOST
SPATA24
SPEF1
SPON2
STAMBPL1
SYT16
TBCEL
TBX3
TCEANC
THAP10
THG1L
TNFAIP8
TNFAIP8L1
TP53BP2
TRAF6
TRAM1L1
TRAPPC3
TRIAP1
TRIM22
TSC22D3
TTC9C
TXNL4B
UBE2Z
UGP2
USF1
XCR1
XRN2
YIF1A
YY1
ZBTB6
ZDHHC24
ZFYVE26
ZNF165
ZNF250
ZNF263
ZNF398
ZNF439
ZNF581
Entrez ID
57332
79666
HPRD ID
13006
15147
Ensembl ID
ENSG00000141570
ENSG00000175895
Uniprot IDs
Q9HC52
Q9H8W4
PDB IDs
2N4Q
3I91
5EQ0
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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