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CBX8 and ZRANB1
Data Source:
BioGRID
(two hybrid)
CBX8
ZRANB1
Description
chromobox 8
zinc finger RANBP2-type containing 1
Image
GO Annotations
Cellular Component
Chromatin
Heterochromatin
Nucleus
Nucleoplasm
PcG Protein Complex
PRC1 Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
Molecular Function
Single-stranded RNA Binding
Protein Binding
Methylated Histone Binding
Ubiquitin-protein Transferase Activator Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cysteine-type Peptidase Activity
Metal Ion Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Cell Population Proliferation
Histone Ubiquitination
Positive Regulation Of Collagen Biosynthetic Process
Positive Regulation Of DNA Repair
Regulation Of Catalytic Activity
Cellular Response To Hydrogen Peroxide
Cytoskeleton Organization
Wnt Signaling Pathway
Cell Migration
Protein Deubiquitination
Protein Phosphopantetheinylation
Regulation Of Cell Morphogenesis
Positive Regulation Of Wnt Signaling Pathway
Protein K29-linked Deubiquitination
Protein K63-linked Deubiquitination
Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein K33-linked Deubiquitination
Pathways
Oxidative Stress Induced Senescence
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription cofactors
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA methylation proteins
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Degradation of beta-catenin by the destruction complex
Ovarian tumor domain proteases
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
General risk tolerance (MTAG) (
30643258
)
Plateletcrit (
32888494
)
Risk-taking tendency (4-domain principal component model) (
30643258
)
Smoking status (ever vs never smokers) (
30643258
)
Youthful appearance (self-reported) (
32339537
)
Blood urea nitrogen levels (
31152163
)
Creatine kinase levels (
29403010
)
Height (
25429064
31562340
)
Interacting Genes
87 interacting genes:
ABLIM3
BACH2
BANP
BMI1
CALCOCO2
CARD10
CARD9
CCDC136
CCDC57
CEP70
DVL3
EEF1G
FHL3
FSD2
FXR1
GIGYF1
GOLGA2
GOLGA6L9
GPRASP2
GRIPAP1
H3-4
HAP1
HMBOX1
HOMEZ
HOOK2
HSF2BP
IKZF1
JADE2
JAKMIP1
KANK2
KAT5
KAT7
KCTD9
KIFC3
KRT31
KRT34
KRT40
LSM2
LZTS2
MB21D2
MCC
MDFI
MID2
MLLT1
MLLT3
MTUS2
NAB2
PAXIP1
PCGF5
PHACTR1
PIBF1
PICK1
PIH1D2
PLEKHF2
PNMA1
PNMA2
POLR1C
PRDM6
PRKAR1B
RASSF3
RING1
RPGRIP1
SESTD1
SETDB1
SOX5
TAX1BP1
TEPSIN
TFCP2
TFIP11
TRAF2
TRIB3
TRIM23
TRIM27
TRIM54
TSC22D4
TSGA10
TTC23
UNC119
USH1G
USP11
USP7
VIM
ZBTB14
ZBTB8A
ZBTB9
ZNF185
ZRANB1
153 interacting genes:
AKT1
ANKRD11
AP1M1
ARHGEF5
ARRDC2
ARRDC3
BAHD1
BRD1
BYSL
C1orf35
CARD9
CBX7
CBX8
CCDC120
CCDC13
CCDC185
CCDC187
CCNL1
CDC45
CDC5L
CDK18
CDKL3
CNNM3
CORO7
CPNE7
CSNK1A1
CWF19L2
DCX
DDX6
DNAJB13
DTNB
DUSP13
EHHADH
EIF3D
ENKD1
ERF
FAIM
FAM124B
FAM161A
FAM161B
FAM214B
FAM50B
FARS2
FNDC11
GADD45GIP1
GAS2L2
GEM
GLIS2
GPANK1
GPKOW
HOXB5
HOXC8
IL16
INO80B
IP6K3
IQUB
JRK
KANK2
KIF9
KIFC3
LENG1
LMO3
LNX1
MAGEB4
MAGOH
MCRS1
METAP1
METTL21A
MFAP1
MID2
MPPED1
MYEF2
NEK6
NUDT16L1
NUDT21
PBLD
PHF1
PHF19
PKN1
PLEKHN1
PNMA5
POLDIP3
POLL
POLR1C
PPP1R18
PRPF18
PRPF3
PRPF31
PSPC1
QARS1
RAPGEF3
RASAL3
RHOBTB3
RNPS1
SDCBP
SNCA
STAMBPL1
STK19
SUV39H1
SYT17
SYTL4
TBC1D3
TBC1D30
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3K
TCEA2
TCEANC
THAP7
TIE1
TLE5
TNS4
TOLLIP
TRAF3IP3
TRAF4
TRAF6
TRAPPC2
TRAPPC2B
TSGA10IP
TSPYL4
TSTD2
TWIST1
UBASH3A
UBC
UBE2S
USP2
UVRAG
VAV3
VEZF1
WT1
XRCC5
ZBTB24
ZBTB47
ZNF124
ZNF17
ZNF250
ZNF408
ZNF417
ZNF438
ZNF490
ZNF497
ZNF552
ZNF575
ZNF581
ZNF587
ZNF599
ZNF629
ZNF648
ZNF764
ZNF775
ZNF792
ZNF837
Entrez ID
57332
54764
HPRD ID
13006
11738
Ensembl ID
ENSG00000141570
ENSG00000019995
Uniprot IDs
Q9HC52
Q9UGI0
PDB IDs
2N4Q
3I91
5EQ0
3ZRH
5AF6
Enriched GO Terms of Interacting Partners
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