CBX8 and BANP

Data Source:
BioGRID (two hybrid)

		CBX8	BANP
Description		chromobox 8	BTG3 associated nuclear protein
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleoplasm Nuclear Body
	Molecular Function	Single-stranded RNA Binding Protein Binding Methylated Histone Binding Ubiquitin-protein Transferase Activator Activity	DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Population Proliferation Histone Ubiquitination Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of DNA Repair Regulation Of Catalytic Activity Cellular Response To Hydrogen Peroxide	Chromatin Organization Cell Cycle Multicellular Organism Development Protein Localization To Nucleus Negative Regulation Of Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Oxidative Stress Induced Senescence SUMOylation of DNA damage response and repair proteins SUMOylation of transcription cofactors SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA methylation proteins RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of PTEN gene transcription Regulation of PTEN gene transcription	Regulation of TP53 Activity through Association with Co-factors
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) General risk tolerance (MTAG) ( 30643258) Plateletcrit ( 32888494) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Youthful appearance (self-reported) ( 32339537)	Apolipoprotein A1 levels ( 32203549) Central corneal thickness ( 28171582 20719862) Corneal structure ( 23291589) HDL cholesterol levels ( 32203549) Intraocular pressure ( 29235454) Mean spheric corpuscular volume ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549)
Interacting Genes		87 interacting genes: ABLIM3 BACH2 BANP BMI1 CALCOCO2 CARD10 CARD9 CCDC136 CCDC57 CEP70 DVL3 EEF1G FHL3 FSD2 FXR1 GIGYF1 GOLGA2 GOLGA6L9 GPRASP2 GRIPAP1 H3-4 HAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKZF1 JADE2 JAKMIP1 KANK2 KAT5 KAT7 KCTD9 KIFC3 KRT31 KRT34 KRT40 LSM2 LZTS2 MB21D2 MCC MDFI MID2 MLLT1 MLLT3 MTUS2 NAB2 PAXIP1 PCGF5 PHACTR1 PIBF1 PICK1 PIH1D2 PLEKHF2 PNMA1 PNMA2 POLR1C PRDM6 PRKAR1B RASSF3 RING1 RPGRIP1 SESTD1 SETDB1 SOX5 TAX1BP1 TEPSIN TFCP2 TFIP11 TRAF2 TRIB3 TRIM23 TRIM27 TRIM54 TSC22D4 TSGA10 TTC23 UNC119 USH1G USP11 USP7 VIM ZBTB14 ZBTB8A ZBTB9 ZNF185 ZRANB1	194 interacting genes: ABLIM3 ADAM15 AFG1L ALAS2 ANAPC11 ANKRD55 ANTKMT ARID5A ATF2 ATXN7L2 BAG5 BICRAL BLZF1 BOC BTG3 C1orf94 C1QTNF2 C22orf15 C22orf39 C2orf83 C3orf36 C4orf45 CAMK2D CBX8 CCDC26 CCDC74B CDC7 CDSN CDX4 CEP76 CFAP206 CHRDL2 COL10A1 CRX CSNK2B CTSZ CYTOR DCDC2B DLX3 DNAJA4 ENKD1 EPHA10 ESM1 FAM117B FAM120C FAM217B FAM222B FAM71C FAM90A1 FARS2 FHL2 FHL5 FLOT1 FOXM1 FOXR1 GAS2L2 GFM2 GOLGA6L9 HAPLN2 HEYL HHIPL1 HIVEP1 HMGB3P1 HNRNPLL HSFY1 IDO2 IGF1 IGFN1 INO80B ISCU KCTD9 KHDC4 KLF15 KRTAP8-1 L3MBTL3 LAP3 LENG1 LGALS14 LGALS4 LHX4 LHX8 LIN54 LINC01547 LMO1 LMO2 LMO3 LMO4 LRIF1 LSM2 MAP2K1 MAPK1 MAX MDFI MEOX1 MEOX2 MIR4435-2HG MRPL28 MRRF MSRB3 MTERF4 MVP NEDD9 NFYA NMNAT1 NOTO NRIP2 PANX2 PARD6B PAX6 PHF21A PHF21B PID1 PIH1D2 PIK3C2G PIM1 PML PNRC2 POGZ POLDIP3 POLR2L POU6F2 PPIB PPIC PPIF PRDM6 PRKAB2 PRKCH PRPF39 PRR20A PRR20B PRR20C PRR20D PRR20E PRR23B PRR34 PSMD9 PSORS1C2 RAB3IP RAD54L2 RBM39 RBPMS REL RELA RHNO1 RHOH RHOQ RIDA RIMS3 RPP25 RYBP SAPCD1 SCN5A SH3RF2 SLC16A3 SNAPIN SNRPB SNX5 SP2 SP4 SPACA6 SPANXN2 SRARP STK38 STOX1 TAF6 TERF2 TERF2IP TNXB TOX TOX4 TP53 TRAF2 TRAF4 TRIM35 TROAP TTC23 UBAP2 UBE2I VEZF1 VMAC XAGE1B YJU2 ZBTB4 ZC2HC1C ZMIZ2 ZMYM6 ZNF410 ZNF438 ZNF471 ZNF474 ZNF488 ZNF512B ZNF580 ZNF581
Entrez ID		57332	54971
HPRD ID		13006	16538
Ensembl ID		ENSG00000141570	ENSG00000172530
Uniprot IDs		Q9HC52	A0A0S2Z5C2 A0A0S2Z5G4 A0A0S2Z5M2 B3KM38 B4DE54 Q8N9N5 Q9NSS6
PDB IDs		2N4Q 3I91 5EQ0
Enriched GO Terms of Interacting Partners?
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