PLEKHF2 and THG1L

Data Source:
BioGRID (two hybrid)

		PLEKHF2	THG1L
Description		pleckstrin homology and FYVE domain containing 2	tRNA-histidine guanylyltransferase 1 like
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Transport Vesicle Early Endosome Membrane	Mitochondrion Mitochondrial Outer Membrane Cytosol Transferase Complex
	Molecular Function	Protein Binding Phosphatidylinositol Binding Metal Ion Binding	TRNA Binding Magnesium Ion Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding GTP Binding TRNA Guanylyltransferase Activity Nucleotidyltransferase Activity Identical Protein Binding
	Biological Process	Protein Transport	TRNA Modification Response To Oxidative Stress TRNA Processing Mitochondrial Fusion Regulation Of Catalytic Activity Protein Homotetramerization TRNA 5'-end Processing Stress-induced Mitochondrial Fusion
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Radiation response ( 20923822)	Red cell distribution width ( 32888494)
Interacting Genes		168 interacting genes: ABCG4 ACY3 ADAP1 AIDA AIMP2 ANO9 APP APPL1 ARID4B ARL14EP ASPH BARHL2 BCAS2 BCAS3 BEND7 BLOC1S6 BOD1 BRD7 BSCL2 C11orf45 C1orf35 C3 CAVIN2 CBX8 CCDC146 CCDC172 CCDC25 CCDC85B CDC20B CEP44 CERK CGGBP1 CHCHD2 CHIC2 COX5B CRYBA1 DAZAP2 DMRT3 DNAAF11 DOCK2 DOCK3 DPPA4 DRAP1 DTX2 DUSP4 DUT EIF3C EML2 EXOC7 FAH FBXO28 FBXW5 FGF13 FHL3 FLNA FRMD8 GAGE12G GAGE2E GEM GFER GLUL GNMT GPBP1 GPBP1L1 GRAMD4 GTPBP2 HEBP2 HSPB7 INO80 KCNAB3 KRTAP10-10 KRTAP5-4 L3MBTL3 LDOC1 MAGI2 MAP2K1 MAX MBIP MBP MEAF6 MFAP1 MIDN MPP4 MRI1 NDUFA5 NFIA NONO NPM2 NSD2 NUDT2 NUTM1 P2RX7 PACSIN1 PAK1IP1 PDK4 PIK3R3 PPCDC PPP1R18 PRDM14 PRKAG1 PRKAR1A PRPSAP1 PTPN3 PWWP2A RAB28 RABAC1 RADX RARA RASGEF1B RGS10 RGS8 RPAP2 RPE RPRM RPS21 RSPO2 RTN1 RTN3 RTN4 S100A1 S100A13 SAMD11 SCYL1 SEC14L4 SEPTIN2 SEPTIN5 SEPTIN6 SETBP1 SFN SNRNP35 SOST SPATA24 SPEF1 SPON2 STAMBPL1 SYT16 TBCEL TBX3 TCEANC THAP10 THG1L TNFAIP8 TNFAIP8L1 TP53BP2 TRAF6 TRAM1L1 TRAPPC3 TRIAP1 TRIM22 TSC22D3 TTC9C TXNL4B UBE2Z UGP2 USF1 XCR1 XRN2 YIF1A YY1 ZBTB6 ZDHHC24 ZFYVE26 ZNF165 ZNF250 ZNF263 ZNF398 ZNF439 ZNF581	7 interacting genes: ELMOD1 LNX1 NTAQ1 PLEKHF2 SDCBP TERF1 UBC
Entrez ID		79666	54974
HPRD ID		15147	13726
Ensembl ID		ENSG00000175895	ENSG00000113272
Uniprot IDs		Q9H8W4	B4E366 Q9H8R6 Q9NWX6
PDB IDs			3OTB 3OTC 3OTD 3OTE
Enriched GO Terms of Interacting Partners?
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