ZRANB1 and SYTL4

Data Source:
BioGRID (two hybrid)

		ZRANB1	SYTL4
Description		zinc finger RANBP2-type containing 1	synaptotagmin like 4
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle	Endosome Plasma Membrane Extrinsic Component Of Membrane Transport Vesicle Membrane Platelet Alpha Granule Membrane Exocytic Vesicle
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Cysteine-type Peptidase Activity Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding	Protein Binding Phospholipid Binding Neurexin Family Protein Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Wnt Signaling Pathway Cell Migration Protein Deubiquitination Protein Phosphopantetheinylation Regulation Of Cell Morphogenesis Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Protein K63-linked Deubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein K33-linked Deubiquitination	Plasma Membrane Repair Platelet Degranulation Intracellular Protein Transport Exocytosis Lysosome Localization Positive Regulation Of Exocytosis Negative Regulation Of Insulin Secretion Positive Regulation Of Protein Secretion Multivesicular Body Sorting Pathway Regulation Of Plasma Membrane Repair
Pathways		Degradation of beta-catenin by the destruction complex Ovarian tumor domain proteases	Platelet degranulation
Drugs			Insulin pork
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Creatine kinase levels ( 29403010) Height ( 25429064 31562340)	Lean body mass ( 28552196) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494)
Interacting Genes		153 interacting genes: AKT1 ANKRD11 AP1M1 ARHGEF5 ARRDC2 ARRDC3 BAHD1 BRD1 BYSL C1orf35 CARD9 CBX7 CBX8 CCDC120 CCDC13 CCDC185 CCDC187 CCNL1 CDC45 CDC5L CDK18 CDKL3 CNNM3 CORO7 CPNE7 CSNK1A1 CWF19L2 DCX DDX6 DNAJB13 DTNB DUSP13 EHHADH EIF3D ENKD1 ERF FAIM FAM124B FAM161A FAM161B FAM214B FAM50B FARS2 FNDC11 GADD45GIP1 GAS2L2 GEM GLIS2 GPANK1 GPKOW HOXB5 HOXC8 IL16 INO80B IP6K3 IQUB JRK KANK2 KIF9 KIFC3 LENG1 LMO3 LNX1 MAGEB4 MAGOH MCRS1 METAP1 METTL21A MFAP1 MID2 MPPED1 MYEF2 NEK6 NUDT16L1 NUDT21 PBLD PHF1 PHF19 PKN1 PLEKHN1 PNMA5 POLDIP3 POLL POLR1C PPP1R18 PRPF18 PRPF3 PRPF31 PSPC1 QARS1 RAPGEF3 RASAL3 RHOBTB3 RNPS1 SDCBP SNCA STAMBPL1 STK19 SUV39H1 SYT17 SYTL4 TBC1D3 TBC1D30 TBC1D3B TBC1D3C TBC1D3G TBC1D3K TCEA2 TCEANC THAP7 TIE1 TLE5 TNS4 TOLLIP TRAF3IP3 TRAF4 TRAF6 TRAPPC2 TRAPPC2B TSGA10IP TSPYL4 TSTD2 TWIST1 UBASH3A UBC UBE2S USP2 UVRAG VAV3 VEZF1 WT1 XRCC5 ZBTB24 ZBTB47 ZNF124 ZNF17 ZNF250 ZNF408 ZNF417 ZNF438 ZNF490 ZNF497 ZNF552 ZNF575 ZNF581 ZNF587 ZNF599 ZNF629 ZNF648 ZNF764 ZNF775 ZNF792 ZNF837	27 interacting genes: CCDC85B CEP70 DVL3 FCHO1 FXR2 HMG20A INS KIFC3 LMO1 LZTS1 OSBPL3 PRKAR1B RAB27A RAB27B RAB3A RAB3D RAB8A ROPN1 SPANXN2 STX1A STXBP1 TBC1D1 TRIM37 TRIM41 ZBTB7B ZBTB9 ZRANB1
Entrez ID		54764	94121
HPRD ID		11738	06735
Ensembl ID		ENSG00000019995	ENSG00000102362
Uniprot IDs		Q9UGI0	A0A024RCF8 A8K973 B2R7R4 Q71SF7 Q96C24
PDB IDs		3ZRH 5AF6	2CSZ 3FDW 5X6T
Enriched GO Terms of Interacting Partners?
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