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ZRANB1 and RAPGEF3
Data Source:
BioGRID
(two hybrid)
ZRANB1
RAPGEF3
Description
zinc finger RANBP2-type containing 1
Rap guanine nucleotide exchange factor 3
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Intracellular Membrane-bounded Organelle
Plasma Membrane
Microvillus
Endomembrane System
Membrane
Lamellipodium
Filopodium
Cortical Actin Cytoskeleton
Extracellular Exosome
Molecular Function
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Cysteine-type Peptidase Activity
Metal Ion Binding
K63-linked Polyubiquitin Modification-dependent Protein Binding
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Protein Domain Specific Binding
CAMP Binding
Biological Process
Cytoskeleton Organization
Wnt Signaling Pathway
Cell Migration
Protein Deubiquitination
Protein Phosphopantetheinylation
Regulation Of Cell Morphogenesis
Positive Regulation Of Wnt Signaling Pathway
Protein K29-linked Deubiquitination
Protein K63-linked Deubiquitination
Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein K33-linked Deubiquitination
Angiogenesis
Signal Transduction
CAMP-mediated Signaling
Rap Protein Signal Transduction
Positive Regulation Of Peptidyl-serine Phosphorylation
Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion
Positive Regulation Of GTPase Activity
Positive Regulation Of Angiogenesis
Positive Regulation Of Protein Export From Nucleus
Regulation Of Insulin Secretion
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion
Establishment Of Endothelial Barrier
Cellular Response To CAMP
Positive Regulation Of Protein Acetylation
Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Histone H3-K9 Acetylation
Pathways
Degradation of beta-catenin by the destruction complex
Ovarian tumor domain proteases
Integrin signaling
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Rap1 signalling
Regulation of insulin secretion
Drugs
Diseases
GWAS
Blood urea nitrogen levels (
31152163
)
Creatine kinase levels (
29403010
)
Height (
25429064
31562340
)
Bipolar disorder (
31043756
)
Body mass index (
29273807
)
Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) (
30940143
)
Platelet distribution width (
32888494
)
Waist-to-hip ratio adjusted for BMI (additive genetic model) (
30778226
)
Interacting Genes
153 interacting genes:
AKT1
ANKRD11
AP1M1
ARHGEF5
ARRDC2
ARRDC3
BAHD1
BRD1
BYSL
C1orf35
CARD9
CBX7
CBX8
CCDC120
CCDC13
CCDC185
CCDC187
CCNL1
CDC45
CDC5L
CDK18
CDKL3
CNNM3
CORO7
CPNE7
CSNK1A1
CWF19L2
DCX
DDX6
DNAJB13
DTNB
DUSP13
EHHADH
EIF3D
ENKD1
ERF
FAIM
FAM124B
FAM161A
FAM161B
FAM214B
FAM50B
FARS2
FNDC11
GADD45GIP1
GAS2L2
GEM
GLIS2
GPANK1
GPKOW
HOXB5
HOXC8
IL16
INO80B
IP6K3
IQUB
JRK
KANK2
KIF9
KIFC3
LENG1
LMO3
LNX1
MAGEB4
MAGOH
MCRS1
METAP1
METTL21A
MFAP1
MID2
MPPED1
MYEF2
NEK6
NUDT16L1
NUDT21
PBLD
PHF1
PHF19
PKN1
PLEKHN1
PNMA5
POLDIP3
POLL
POLR1C
PPP1R18
PRPF18
PRPF3
PRPF31
PSPC1
QARS1
RAPGEF3
RASAL3
RHOBTB3
RNPS1
SDCBP
SNCA
STAMBPL1
STK19
SUV39H1
SYT17
SYTL4
TBC1D3
TBC1D30
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3K
TCEA2
TCEANC
THAP7
TIE1
TLE5
TNS4
TOLLIP
TRAF3IP3
TRAF4
TRAF6
TRAPPC2
TRAPPC2B
TSGA10IP
TSPYL4
TSTD2
TWIST1
UBASH3A
UBC
UBE2S
USP2
UVRAG
VAV3
VEZF1
WT1
XRCC5
ZBTB24
ZBTB47
ZNF124
ZNF17
ZNF250
ZNF408
ZNF417
ZNF438
ZNF490
ZNF497
ZNF552
ZNF575
ZNF581
ZNF587
ZNF599
ZNF629
ZNF648
ZNF764
ZNF775
ZNF792
ZNF837
14 interacting genes:
AP1M1
AP2B1
DAPK1
DDX6
EXOC8
MAP1A
OARD1
PNMA1
RAP1A
RAP2A
RRAS2
TGFB1
UFSP1
ZRANB1
Entrez ID
54764
10411
HPRD ID
11738
06928
Ensembl ID
ENSG00000019995
ENSG00000079337
Uniprot IDs
Q9UGI0
O95398
Q99777
PDB IDs
3ZRH
5AF6
6H7E
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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