ATP13A1 and TMBIM6

Data Source:
BioGRID (two hybrid)

		ATP13A1	TMBIM6
Description		ATPase 13A1	transmembrane BAX inhibitor motif containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Molecular_function ATP Binding Manganese Transmembrane Transporter Activity, Phosphorylative Mechanism ATPase Activity Metal Ion Binding	Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding Endoribonuclease Inhibitor Activity
	Biological Process	Cellular Calcium Ion Homeostasis Biological_process Ion Transmembrane Transport Manganese Ion Transmembrane Transport	Negative Regulation Of Immunoglobulin Production Autophagy Negative Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Protein Binding Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of RNA Splicing Cellular Response To Unfolded Protein Negative Regulation Of Apoptotic Process Negative Regulation Of Endoribonuclease Activity Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Response To L-glutamate Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Signaling Pathway
Pathways		Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Refractive error ( 32231278) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Toenail selenium levels ( 25343990) White blood cell count ( 32888494)	General cognitive ability ( 29844566)
Interacting Genes		31 interacting genes: AGTR1 APPBP2 AQP6 ARHGEF5 BUD31 CBARP CXCR2 EBP ELOVL4 FAM209A FFAR2 GLP1R GPR42 KMT2E MANBAL MFSD14B MMD RNASEK SCN3B SLC10A6 SLC16A13 SLC30A2 SLC30A8 SLC35C2 SYPL2 TLCD4 TMBIM6 TMEM14B TMEM237 UNC93A VMA21	68 interacting genes: ADIPOR2 ATP13A1 BCL2 BCL2L1 CD300LG CD79A CD99L2 CDC7 CERS2 CLDN22 COBLL1 CREB3L1 EBP ENPP4 ERP29 ESAM FAM209A FERD3L FGFBP2 FXYD3 GJA5 GJA8 GJB4 GLP1R GPHB5 GPR151 GPR42 GPX8 GYPA GZMK HERPUD2 HJV HTR2C IER3 JSRP1 KCNA10 KCNC1 LIME1 LRRC59 MANBAL MFSD14B MMGT1 MS4A3 ODF4 OPRM1 PI16 PIANP PVR REEP2 RHBDL2 RNF185 SCN3B SIT1 SLAMF6 SLC12A7 SLC41A3 SLC7A1 SOAT2 STEAP1B SYT9 TEX29 TMEM31 TMUB1 TMX2 TNFRSF17 TREML1 UGT2B11 VTI1A
Entrez ID		57130	7009
HPRD ID		12501	02851
Ensembl ID		ENSG00000105726	ENSG00000139644
Uniprot IDs		A0A024R7N2 Q9HD20	A0A024R0Z5 P55061
PDB IDs
Enriched GO Terms of Interacting Partners?
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