TMEM109 and SPINT1

Data Source:
BioGRID (two hybrid)

		TMEM109	SPINT1
Description		transmembrane protein 109	serine peptidase inhibitor, Kunitz type 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Outer Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Membrane Extracellular Exosome	Extracellular Region Extracellular Space Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Molecular_function Voltage-gated Ion Channel Activity Protein Binding	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Cell Death Cellular Response To Gamma Radiation	Neural Tube Closure Negative Regulation Of Endopeptidase Activity Extracellular Matrix Organization Positive Regulation Of Glial Cell Differentiation Branching Involved In Labyrinthine Layer Morphogenesis Placenta Blood Vessel Development Cellular Response To BMP Stimulus Negative Regulation Of Neural Precursor Cell Proliferation
Pathways			MET Receptor Activation Signaling by MST1
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Malaria ( 31844061) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		16 interacting genes: AQP2 AQP9 ERGIC3 GOLM1 GPX8 LMNA MGST3 MTIF3 PDZK1IP1 RNF170 SAR1A SLC18A2 SPINT1 STOM TMEM52B TMEM80	23 interacting genes: ADAM33 AGR3 CLDN11 CLEC7A FAM3C HGFAC HMGB1 KRTAP1-3 MAL NLGN3 SLC38A7 SMCO4 ST14 TENT5A TF TMEM109 TMEM190 TMEM97 TSPAN33 UBQLN2 UBQLN4 UPK1B VAMP5
Entrez ID		79073	6692
HPRD ID		14687	05494
Ensembl ID		ENSG00000110108	ENSG00000166145
Uniprot IDs		Q9BVC6	O43278
PDB IDs			1YC0 2MSX 4ISL 4ISN 4ISO 5EZD 5H7V
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?