JUNB and JDP2

Data Source:
HPRD (in vitro, in vivo)

		JUNB	JDP2
Description		JunB proto-oncogene, AP-1 transcription factor subunit	Jun dimerization protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleoplasm Transcription Regulator Complex Transcription Factor AP-1 Complex	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin Binding Protein Binding Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Cytokine-mediated Signaling Pathway Osteoclast Differentiation Osteoblast Proliferation Regulation Of Cell Population Proliferation Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Decidualization Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Histone Deacetylation Negative Regulation Of Fat Cell Differentiation
Pathways		SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription NGF-stimulated transcription
Drugs			Pseudoephedrine
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Basal cell carcinoma ( 31174203) Keratinocyte cancer (MTAG) ( 31174203) Multiple sclerosis ( 24076602) Obesity-related traits ( 23251661) Periodontal microbiota ( 22699663)
Interacting Genes		39 interacting genes: APLP2 ATF4 BATF BATF2 BCL6 BDNF BRCA1 DDIT3 DNMT3L EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 ITCH JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG UBA6 UBE2I USP24 ZNF595 ZSWIM9	22 interacting genes: ATF2 ATF4 CREB5 CREBBP DDIT3 EP300 GTF2H1 HDAC1 HDAC4 HDAC5 HDAC6 IRF2BP1 JUN JUNB JUND KAT2B MAPK14 MAPK8 MAPK9 PGR SNW1 TP53
Entrez ID		3726	122953
HPRD ID		01303	16360
Ensembl ID		ENSG00000171223	ENSG00000140044
Uniprot IDs		P17275 Q5U079	A0A024R6D7 Q8WYK2
PDB IDs
Enriched GO Terms of Interacting Partners?
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