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PIAS4 and RIF1
Data Source:
BioGRID
(affinity chromatography technology)
HPRD
(two hybrid)
PIAS4
RIF1
Description
protein inhibitor of activated STAT 4
replication timing regulatory factor 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Matrix
PML Body
Transferase Complex
Chromosome, Telomeric Region
Chromatin
Condensed Chromosome
Female Pronucleus
Male Pronucleus
Nucleus
Nucleoplasm
Cytoplasm
Plasma Membrane
Nuclear Body
Nuclear Membrane
Site Of Double-strand Break
Spindle Midzone
Molecular Function
RNA Polymerase II Transcription Factor Binding
DNA Binding
Transcription Coregulator Activity
Transcription Corepressor Activity
Protein Binding
Protein C-terminus Binding
Zinc Ion Binding
SUMO Transferase Activity
Ubiquitin Protein Ligase Binding
SUMO Ligase Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Double-strand Break Repair Via Nonhomologous End Joining
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Wnt Signaling Pathway
Protein Sumoylation
Negative Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Protein Sumoylation
Vitamin D Metabolic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Keratinocyte Apoptotic Process
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Negative Regulation Of Transcription By RNA Polymerase II
Telomere Maintenance
Double-strand Break Repair Via Nonhomologous End Joining
Chromatin Silencing At Telomere
Cellular Response To DNA Damage Stimulus
Cell Cycle
Stem Cell Population Maintenance
Telomere Maintenance In Response To DNA Damage
Positive Regulation Of Isotype Switching
Positive Regulation Of Histone H3-K9 Methylation
Cellular Response To Leukemia Inhibitory Factor
Negative Regulation Of Double-strand Break Repair Via Homologous Recombination
Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
Vitamin D (calciferol) metabolism
SUMOylation of DNA damage response and repair proteins
SUMOylation of transcription factors
SUMOylation of ubiquitinylation proteins
SUMOylation of transcription cofactors
SUMOylation of SUMOylation proteins
SUMOylation of intracellular receptors
SUMOylation of intracellular receptors
SUMOylation of DNA replication proteins
SUMOylation of immune response proteins
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Nonhomologous End-Joining (NHEJ)
Processing of DNA double-strand break ends
G2/M DNA damage checkpoint
Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
28165464
)
HDL cholesterol levels (
32203549
)
Refractive error (
32231278
)
Lung cancer (
23143601
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Metabolite levels (
23823483
)
Interacting Genes
85 interacting genes:
ACTN1
ALDOA
AR
AREL1
BARD1
BRCA1
BTAF1
CALCOCO2
CEBPD
CHD3
CLK1
COIL
ESRRA
FTH1
GADD45G
HDAC1
HDAC2
HNF4A
HNRNPUL1
HTT
IL15RA
IMMT
IMPDH2
IRF3
IRF7
KNTC1
KPNB1
KRT18
LAMP2
LCE1D
LEF1
LRIF1
MAGEH1
MAP1LC3A
MDC1
MPRIP
NEFL
NR4A2
OAZ1
OPTN
PARP1
PDE4A
PDE4D
PDE4DIP
PHF11
PHGDH
PIAS1
PIAS2
PLAG1
PRKCZ
PRPF40A
PTN
RIF1
SATB1
SERBP1
SERPINA5
SETDB1
SH3GL3
SKIL
SMAD1
SMAD2
SMAD3
SMAD4
SMAD7
SNAI2
SNIP1
SUMO1
SUMO2
SUMO3
TADA3
TCERG1
TICAM1
TOP2A
TP53
TRIM27
TRIM32
TRIM38
UBE2I
UBE2K
VHL
VIM
ZBTB34
ZHX1
ZNF512B
ZW10
20 interacting genes:
BRD7
CEP126
CHD3
DEFB1
FEZ1
GIT1
GNE
GRB2
HAP1
LINC00839
NSG2
PABPC4
PIAS4
POT1
PPP1CA
PPP1CC
SETDB1
SMARCD1
SUMO2
TERF2IP
Entrez ID
51588
55183
HPRD ID
06910
10603
Ensembl ID
ENSG00000105229
ENSG00000080345
Uniprot IDs
B3KMR4
Q8N2W9
Q5UIP0
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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