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PRKAA2 and TRIP13
Data Source:
BioGRID
(two hybrid)
PRKAA2
TRIP13
Description
protein kinase AMP-activated catalytic subunit alpha 2
thyroid hormone receptor interactor 13
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Neuronal Cell Body
Male Germ Cell Nucleus
Nucleus
Chromosome
Molecular Function
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
AMP-activated Protein Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Histone Serine Kinase Activity
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
[acetyl-CoA Carboxylase] Kinase Activity
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Transcription Coregulator Activity
Protein Binding
ATP Binding
ATPase Activity
Identical Protein Binding
Biological Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cholesterol Biosynthetic Process
Carnitine Shuttle
Cell Cycle Arrest
Signal Transduction
Lipid Biosynthetic Process
Positive Regulation Of Autophagy
Negative Regulation Of Gene Expression
Response To Muscle Activity
Wnt Signaling Pathway
Macroautophagy
Positive Regulation Of Macroautophagy
Regulation Of Macroautophagy
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Cellular Response To Oxidative Stress
Histone-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Drug
Cellular Response To Glucose Starvation
Regulation Of Fatty Acid Biosynthetic Process
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Positive Regulation Of Glycolytic Process
Rhythmic Process
Fatty Acid Homeostasis
Regulation Of Stress Granule Assembly
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Calcium Ion
Cellular Response To Glucose Stimulus
Cellular Response To Prostaglandin E Stimulus
Energy Homeostasis
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Cellular Protein Localization
Negative Regulation Of Tubulin Deacetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Oocyte Maturation
Double-strand Break Repair
Regulation Of Transcription, DNA-templated
Transcription By RNA Polymerase II
Mitotic Spindle Assembly Checkpoint
Synaptonemal Complex Assembly
Reciprocal Meiotic Recombination
Male Meiosis I
Female Meiosis I
Spermatogenesis
Spermatid Development
Oogenesis
Meiotic Recombination Checkpoint
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
AMPK inhibits chREBP transcriptional activation activity
Carnitine metabolism
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Diseases
GWAS
Lymphocyte counts (
22286170
)
Pancreatic cancer (
25086665
)
Interacting Genes
122 interacting genes:
ABI1
ABI2
ACACA
ACACB
AIMP2
AKAP8L
AMOT
AMOTL2
ANAPC11
APPBP2
ARRDC3
AVPI1
C19orf47
CALCOCO1
CALCOCO2
CCDC172
CCDC33
CCNB1IP1
CDC42EP1
CDR2
CDX4
CPSF7
CTAG2
CYSRT1
DNAAF6
DNM2
DNMT1
DVL3
EEF2K
EMILIN1
EPM2A
EPN2
FNDC3B
FOS
GIGYF1
GLI1
GOLGA2
GOLGA6A
GRAP2
HAT1
HMBOX1
HNF4A
HOMEZ
IKZF1
IKZF3
KCTD1
KCTD9
KIAA1328
KIF16B
KIF24
KIFC3
KRT16
KRT31
KRTAP1-3
KRTAP10-3
KRTAP10-9
L3MBTL3
LCN2
LEP
LZTS2
MKRN3
MORN3
MRFAP1
MTUS2
MYCL
MYOZ1
NAB2
NECAB2
NONO
NOTCH2NLA
NRAP
NRBF2
NUTM1
PBXIP1
PFKFB2
PLEKHN1
PPP1R32
PRDM6
PRKAB1
PRKAG1
PRKAR1B
PRKN
PRPH
RASAL3
RBBP7
RBPMS
REL
RFX6
RPTOR
SERTAD3
SKIV2L
SLA2
SNW1
SOHLH1
SPRY1
STAC2
STK11
TCF4
TFAP2A
TIFA
TLE5
TMOD1
TRIP13
TRIP6
TSC22D4
UBE2I
USH1C
USH1G
USHBP1
USP10
VPS28
VPS37B
VPS52
WASHC1
WWP1
WWP2
YPEL3
ZBTB8A
ZMYND12
ZNF212
ZNF397
ZSCAN23
112 interacting genes:
ADAM15
AMDHD2
ANKRD10
ARL11
ARSA
ASB13
BUB1B
C11orf54
C19orf54
C4orf33
CARD14
CD99
CDC20
CDIN1
CEP170B
CFP
CLIP4
COMT
CRMP1
CRYBA2
CYB5R2
DCTN3
DDAH2
DIP2A
DPYSL4
DTX2
EEF2KMT
FBLN5
FBXO8
FNDC3B
GALT
GLYCTK
GPRIN2
GPSM1
HDHD3
IGFN1
IL2RB
INCA1
INTS11
KRTAP12-1
KRTAP12-2
KRTAP12-4
KRTAP26-1
KRTAP3-2
KRTAP6-1
KRTAP6-2
KYAT1
LASP1
LNX1
LOXL4
LRR1
LRRC61
M1AP
MAD2L1
MAD2L1BP
MBLAC1
MEAK7
METTL15
MGAT5B
MORN3
MPPED2
MVP
MYEOV
NIF3L1
NME4
NTAQ1
PARP11
PAX9
PBLD
PCMTD2
PCSK5
PELI1
PLAC8
PLK3
PLSCR3
PLSCR4
POLR2L
PPP2CA
PRKAA2
PRKN
PRR13
PSMB8
QARS1
RBPMS
RHOXF2
RNF4
SCP2
SDCBP
SEC24A
SELENBP1
SEMA3B
SEMA4G
SHARPIN
SIGLEC5
SMUG1
SPRYD7
SSC4D
STAMBP
STAMBPL1
SUMO2
TENT5B
TEX37
THRB
TINAGL1
TNRC6A
TPT1
UBE2I
VDR
VENTX
ZMYM5
ZNF34
ZNF655
Entrez ID
5563
9319
HPRD ID
02735
05145
Ensembl ID
ENSG00000162409
ENSG00000071539
Uniprot IDs
P54646
Q15645
PDB IDs
2H6D
2LTU
2YZA
3AQV
4CFE
4CFF
4ZHX
5EZV
5ISO
6B1U
6B2E
6BX6
5VQ9
5VQA
5WC2
6F0X
6LK0
Enriched GO Terms of Interacting Partners
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