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PRKAA2 and KCTD9
Data Source:
BioGRID
(two hybrid)
PRKAA2
KCTD9
Description
protein kinase AMP-activated catalytic subunit alpha 2
potassium channel tetramerization domain containing 9
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Cytosol
Cytoplasmic Stress Granule
Nuclear Speck
Axon
Dendrite
Neuronal Cell Body
Molecular Function
Chromatin Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
AMP-activated Protein Kinase Activity
Protein Serine/threonine/tyrosine Kinase Activity
Protein Binding
ATP Binding
Histone Serine Kinase Activity
Metal Ion Binding
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
[acetyl-CoA Carboxylase] Kinase Activity
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Protein Binding
Identical Protein Binding
Protein Self-association
Cullin Family Protein Binding
Biological Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Cholesterol Biosynthetic Process
Carnitine Shuttle
Cell Cycle Arrest
Signal Transduction
Lipid Biosynthetic Process
Positive Regulation Of Autophagy
Negative Regulation Of Gene Expression
Response To Muscle Activity
Wnt Signaling Pathway
Macroautophagy
Positive Regulation Of Macroautophagy
Regulation Of Macroautophagy
Cellular Response To Nutrient Levels
Negative Regulation Of TOR Signaling
Cellular Response To Oxidative Stress
Histone-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Drug
Cellular Response To Glucose Starvation
Regulation Of Fatty Acid Biosynthetic Process
Glucose Homeostasis
Regulation Of Circadian Rhythm
Negative Regulation Of Apoptotic Process
Positive Regulation Of Glycolytic Process
Rhythmic Process
Fatty Acid Homeostasis
Regulation Of Stress Granule Assembly
Regulation Of Microtubule Cytoskeleton Organization
Cellular Response To Calcium Ion
Cellular Response To Glucose Stimulus
Cellular Response To Prostaglandin E Stimulus
Energy Homeostasis
Regulation Of Signal Transduction By P53 Class Mediator
Positive Regulation Of Cellular Protein Localization
Negative Regulation Of Tubulin Deacetylation
Positive Regulation Of Peptidyl-lysine Acetylation
Protein Ubiquitination
Intracellular Signal Transduction
Protein Homooligomerization
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
AMPK inhibits chREBP transcriptional activation activity
AMPK inhibits chREBP transcriptional activation activity
Carnitine metabolism
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Diseases
GWAS
Lymphocyte counts (
22286170
)
Lymphocyte counts (
32888494
)
Monocyte count (
32888494
)
Interacting Genes
122 interacting genes:
ABI1
ABI2
ACACA
ACACB
AIMP2
AKAP8L
AMOT
AMOTL2
ANAPC11
APPBP2
ARRDC3
AVPI1
C19orf47
CALCOCO1
CALCOCO2
CCDC172
CCDC33
CCNB1IP1
CDC42EP1
CDR2
CDX4
CPSF7
CTAG2
CYSRT1
DNAAF6
DNM2
DNMT1
DVL3
EEF2K
EMILIN1
EPM2A
EPN2
FNDC3B
FOS
GIGYF1
GLI1
GOLGA2
GOLGA6A
GRAP2
HAT1
HMBOX1
HNF4A
HOMEZ
IKZF1
IKZF3
KCTD1
KCTD9
KIAA1328
KIF16B
KIF24
KIFC3
KRT16
KRT31
KRTAP1-3
KRTAP10-3
KRTAP10-9
L3MBTL3
LCN2
LEP
LZTS2
MKRN3
MORN3
MRFAP1
MTUS2
MYCL
MYOZ1
NAB2
NECAB2
NONO
NOTCH2NLA
NRAP
NRBF2
NUTM1
PBXIP1
PFKFB2
PLEKHN1
PPP1R32
PRDM6
PRKAB1
PRKAG1
PRKAR1B
PRKN
PRPH
RASAL3
RBBP7
RBPMS
REL
RFX6
RPTOR
SERTAD3
SKIV2L
SLA2
SNW1
SOHLH1
SPRY1
STAC2
STK11
TCF4
TFAP2A
TIFA
TLE5
TMOD1
TRIP13
TRIP6
TSC22D4
UBE2I
USH1C
USH1G
USHBP1
USP10
VPS28
VPS37B
VPS52
WASHC1
WWP1
WWP2
YPEL3
ZBTB8A
ZMYND12
ZNF212
ZNF397
ZSCAN23
94 interacting genes:
ADAMTSL4
ANKS1A
AQP1
ARID5A
BANP
BLZF1
C19orf54
C7orf31
C9orf24
CARD9
CBX8
CCDC33
CDC37
CDPF1
CFP
CRADD
CUL3
DDIT4L
DEUP1
EHHADH
EPM2AIP1
FAM124B
GEM
GOLGA6A
GOLGA6L9
GORASP2
GPANK1
HOXA1
HOXC8
IGFN1
IL16
INCA1
KIF9
KLHL26
KRT31
KRT34
KRT35
KRT40
KRTAP13-2
KRTAP13-3
LNX1
LONRF1
MAD2L2
MBD3L1
MEOX2
MIIP
MVP
NDUFAB1
NIF3L1
NTAQ1
NUP35
PDZD4
PFDN5
PICK1
PLOD3
PNKD
POF1B
PPP1R16B
PPP1R18
PPP1R32
PRDM6
PRKAA2
PSMA1
PSMB2
RBPMS
RFX6
RUSC1
SDCBP
SKP1
SLAIN1
SMARCB1
SMUG1
SPATS1
SPG21
STX11
SYT6
TASOR2
TEPSIN
TEX37
TNS2
TRIM27
TRIM32
TRIM42
TRIP6
UNKL
USP21
USP54
WDR83
ZBTB25
ZBTB42
ZNF408
ZNF426
ZNF620
ZNF76
Entrez ID
5563
54793
HPRD ID
02735
13772
Ensembl ID
ENSG00000162409
ENSG00000104756
Uniprot IDs
P54646
Q7L273
PDB IDs
2H6D
2LTU
2YZA
3AQV
4CFE
4CFF
4ZHX
5EZV
5ISO
6B1U
6B2E
6BX6
5BXH
Enriched GO Terms of Interacting Partners
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