UNC50 and DARS2

Data Source:
BioGRID (two hybrid)

		UNC50	DARS2
Description		unc-50 inner nuclear membrane RNA binding protein	aspartyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Inner Membrane Integral Component Of Golgi Membrane	Nucleoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	RNA Binding Protein Binding	TRNA Binding Aspartate-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity Aspartate-tRNA(Asn) Ligase Activity
	Biological Process	Transport Protein Transport	TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Mitochondrial Asparaginyl-tRNA Aminoacylation
Pathways			Mitochondrial tRNA aminoacylation
Drugs			Aspartic acid
Diseases			Leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation (LBSL)
GWAS		Diverticular disease ( 30177863)	Hematocrit ( 32888494) Hemoglobin ( 32888494) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		33 interacting genes: AQP6 CLEC10A CLRN1 CREB3 DARS2 EBP ELOVL4 ERGIC3 FAM209A FCER1G FFAR2 FITM2 GPR152 GPX8 HSD17B11 HSD17B13 IFNGR2 KCNJ6 LMNA MFF MFSD14B MGST3 MTIF3 MUC1 REEP4 SAR1A SGPL1 SLC10A1 SLC10A6 TMED8 TMEM14B TMEM167B TMEM234	15 interacting genes: AIMP2 ALDH18A1 AOC3 CDIPT COL8A2 CYB561 DPYSL5 EPHA8 FETUB KARS1 PLP2 THSD7B TMEM239 TSPAN33 UNC50
Entrez ID		25972	55157
HPRD ID		18259	07677
Ensembl ID		ENSG00000115446	ENSG00000117593
Uniprot IDs		A0A0S2Z612 J3KQ47 Q53HI1	Q6PI48 Q9H9J7
PDB IDs			4AH6
Enriched GO Terms of Interacting Partners?
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