RBM23 and POLA2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBM23	POLA2
Description		RNA binding motif protein 23	DNA polymerase alpha 2, accessory subunit
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GO Annotations	Cellular Component	Nucleus Membrane	Nucleoplasm Alpha DNA Polymerase:primase Complex Cytosol
	Molecular Function	RNA Binding Protein Binding	Molecular_function DNA Binding Protein Binding
	Biological Process	MRNA Processing RNA Splicing Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Splicing, Via Spliceosome	G1/S Transition Of Mitotic Cell Cycle DNA Replication DNA Replication, Synthesis Of RNA Primer DNA Replication Initiation Telomere Maintenance Via Semi-conservative Replication
Pathways			Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand
Drugs			Dacarbazine
Diseases
GWAS		Cardiovascular death, myocardial infarction or stroke in response to clopidogrel treatment ( 32472697) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical amyloid beta load ( 29860282) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Acne (severe) ( 24927181) Serum uric acid levels ( 32514006)
Interacting Genes		31 interacting genes: BHLHE40 CDK6 CEP126 CHERP ESR1 FAM9B FBXO7 GTF3C1 KHDC4 MAGEA11 MAGED1 MED31 PGR POLA2 PRMT5 PRR20A PRR20B PRR20C PRR20D PRR20E PTN QKI RBFOX2 RBM25 RBM39 RBM4 RPA1 SRPK1 SRPK2 TRIM27 TUBA4A	33 interacting genes: AKTIP APP ASCC2 ATP5F1C CPE CRELD1 DCP2 DDX24 DHX34 EIF6 EZH2 FAM219A FGFR3 FRZB HDAC6 HELB HGH1 IGFBP3 KCNE3 KLF6 LRPAP1 MFHAS1 NR4A1 PARP1 POLA1 PRIM2 PRPF38A RBM23 SETDB1 SNU13 STK40 ULK2 XPNPEP1
Entrez ID		55147	23649
HPRD ID		15227	10160
Ensembl ID		ENSG00000100461	ENSG00000014138
Uniprot IDs		A0A0S2Z5D9 A0A0S2Z5I1 A0A0S2Z5J3 B7Z8M4 G3XAP0 Q86U06	Q14181
PDB IDs		2CQ4 2DNZ	2KEB 4E2I 4Y97 5EXR
Enriched GO Terms of Interacting Partners?
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