UACA and STAMBP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		UACA	STAMBP
Description		uveal autoantigen with coiled-coil domains and ankyrin repeats	STAM binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytosol Cytoskeleton Extracellular Exosome	Nucleus Nucleoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Cleavage Furrow Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Metallopeptidase Activity Protein Domain Specific Binding Metal Ion Binding Lys63-specific Deubiquitinase Activity Isopeptidase Activity
	Biological Process	Biological_process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Apoptotic Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling	Mitotic Cytokinesis Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Cell Population Proliferation Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Protein Deubiquitination Protein Phosphopantetheinylation Negative Regulation Of Ras Protein Signal Transduction Protein K63-linked Deubiquitination
Pathways		Regulation of the apoptosome activity	Metalloprotease DUBs
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Pulmonary function ( 23932459)	Anti-saccade response ( 29064472) Blood metabolite levels ( 26401656) Serum metabolite levels ( 23093944)
Interacting Genes		13 interacting genes: AHCYL1 ANKRD28 CCDC125 CELSR3 HIF1AN JPH1 KRT31 KRT40 MED14 PRKAR1B RTP2 STAMBP UBQLN2	45 interacting genes: ALAS1 AMN APOBEC3A BMPR1B CASR CHMP1A CHMP1B CHMP2A CHMP3 CHMP4A CHMP4B CHMP4C CHMP5 CLTC CTNNBL1 CYP2C9 EPS15 GRAP2 GRB2 IL1RL2 ITGA5 MAP2K5 MAP3K2 NLRP3 NLRP7 NTPCR PJA1 RECQL5 RNF11 SMAD2 SMAD6 SMAD7 SNCA SPG7 STAM STAM2 TNFRSF1A TP53 TRAF6 TRIP13 UACA UBC UBE2S USP21 USP28
Entrez ID		55075	10617
HPRD ID		11657	05877
Ensembl ID		ENSG00000137831	ENSG00000124356
Uniprot IDs		Q9BZF9	A0A140VK54 O95630
PDB IDs			2XZE 3RZU 3RZV 5IXF
Enriched GO Terms of Interacting Partners?
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