NRDE2 and RCOR3

Data Source:
BioGRID (two hybrid)

		NRDE2	RCOR3
Description		NRDE-2, necessary for RNA interference, domain containing	REST corepressor 3
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Speck	Histone Deacetylase Complex Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	Molecular_function Protein Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	RNA Interference Heterochromatin Assembly By Small RNA Positive Regulation Of RNA Export From Nucleus Negative Regulation Of RNA Catabolic Process	Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Plateletcrit ( 32888494)
Interacting Genes		11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28	74 interacting genes: ABI1 ANKRD11 APP BHLHB9 BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PHF21B PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688
Entrez ID		55051	55758
HPRD ID		12625	08338
Ensembl ID		ENSG00000119720	ENSG00000117625
Uniprot IDs		Q9H7Z3	Q9P2K3
PDB IDs		6IEH	4CZZ
Enriched GO Terms of Interacting Partners?
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