RCOR3 and VAX1

Data Source:
BioGRID (two hybrid)

		RCOR3	VAX1
Description		REST corepressor 3	ventral anterior homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm Transcription Regulator Complex Cytosol	Chromatin Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Intronic Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Chromatin DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Neuroblast Proliferation Axon Guidance Central Nervous System Development Brain Development Neuron Differentiation Skeletal Muscle Cell Differentiation Camera-type Eye Development Roof Of Mouth Development
Pathways
Drugs
Diseases
GWAS		Plateletcrit ( 32888494)	Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545) Cleft lip with or without cleft palate ( 28054174) Nonsyndromic cleft lip ( 31609978) Nonsyndromic cleft lip with cleft palate ( 28232668) Nonsyndromic cleft lip with or without cleft palate ( 25775280) Orofacial clefts ( 20023658 28054174)
Interacting Genes		74 interacting genes: ABI1 ANKRD11 APP BHLHB9 BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PHF21B PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688	14 interacting genes: DVL3 EAF1 ESRRG HECW1 HMBOX1 MLLT3 PICK1 POLR3C PSMB1 RCOR3 RPRD1B SDCBP2 SPANXN2 USP20
Entrez ID		55758	11023
HPRD ID		08338	16052
Ensembl ID		ENSG00000117625	ENSG00000148704
Uniprot IDs		Q9P2K3	Q5SQQ9
PDB IDs		4CZZ
Enriched GO Terms of Interacting Partners?
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