NRDE2 and UQCC2

Data Source:
BioGRID (two hybrid)

		NRDE2	UQCC2
Description		NRDE-2, necessary for RNA interference, domain containing	ubiquinol-cytochrome c reductase complex assembly factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Speck	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Matrix Nuclear Body Mitochondrial Nucleoid
	Molecular Function	Molecular_function Protein Binding	Protein Binding
	Biological Process	RNA Interference Heterochromatin Assembly By Small RNA Positive Regulation Of RNA Export From Nucleus Negative Regulation Of RNA Catabolic Process	Regulation Of Oxidative Phosphorylation Mitochondrial Respiratory Chain Complex III Assembly Regulation Of Insulin Secretion Positive Regulation Of Mitochondrial Translation Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Skeletal Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Asthma and attention deficit hyperactivity disorder ( 31619474) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Gait speed in old age ( 28077804) Hodgkin's lymphoma ( 30194254)
Interacting Genes		11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28	15 interacting genes: CDKN2D CEACAM5 EXOC8 GNG13 GRB2 HSPB1 MKRN3 MRFAP1 NRDE2 RABGAP1L SNAP25 TRAPPC2 TRAPPC2B TXN2 ZNF765
Entrez ID		55051	84300
HPRD ID		12625	12847
Ensembl ID		ENSG00000119720	ENSG00000137288
Uniprot IDs		Q9H7Z3	Q9BRT2
PDB IDs		6IEH
Enriched GO Terms of Interacting Partners?
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