RCOR3 and LCA5

Data Source:
BioGRID (two hybrid, two hybrid)

		RCOR3	LCA5
Description		REST corepressor 3	lebercilin LCA5
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm Transcription Regulator Complex Cytosol	Cilium Axoneme Photoreceptor Connecting Cilium Ciliary Basal Body
	Molecular Function	Transcription Corepressor Activity Protein Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Negative Regulation Of Transcription, DNA-templated	Intraciliary Transport Photoreceptor Cell Maintenance
Pathways
Drugs
Diseases			Leber congenital amaurosis (LCR)
GWAS		Plateletcrit ( 32888494)	Glucose homeostasis traits ( 25524916) Hoarding ( 21302353) Presence of antiphospholipid antibodies ( 23509613)
Interacting Genes		74 interacting genes: ABI1 ANKRD11 APP BHLHB9 BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PHF21B PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688	6 interacting genes: GCC1 RCOR3 SRPK2 SUFU TFIP11 TXLNA
Entrez ID		55758	167691
HPRD ID		08338	10791
Ensembl ID		ENSG00000117625	ENSG00000135338
Uniprot IDs		Q9P2K3	A0A384MDJ7 Q86VQ0
PDB IDs		4CZZ
Enriched GO Terms of Interacting Partners?
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