NRDE2 and HAUS8

Data Source:
BioGRID (two hybrid)

		NRDE2	HAUS8
Description		NRDE-2, necessary for RNA interference, domain containing	HAUS augmin like complex subunit 8
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Nuclear Speck	Spindle Pole Cytoplasm Centrosome Cytosol Nuclear Microtubule HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Molecular_function Protein Binding	Molecular_function Protein Binding Microtubule Binding
	Biological Process	RNA Interference Heterochromatin Assembly By Small RNA Positive Regulation Of RNA Export From Nucleus Negative Regulation Of RNA Catabolic Process	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Mean corpuscular hemoglobin concentration ( 32888494) Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758)
Interacting Genes		11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28	14 interacting genes: APP C1orf216 CCHCR1 DEUP1 HAUS5 HAUS6 HSPB1 NME7 NRDE2 NTAQ1 NUP54 TXN2 USHBP1 ZG16B
Entrez ID		55051	93323
HPRD ID		12625	11318
Ensembl ID		ENSG00000119720	ENSG00000131351
Uniprot IDs		Q9H7Z3	Q9BT25
PDB IDs		6IEH
Enriched GO Terms of Interacting Partners?
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