RCOR3 and PTTG2

Data Source:
BioGRID (two hybrid)

		RCOR3	PTTG2
Description		REST corepressor 3	pituitary tumor-transforming 2
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm Transcription Regulator Complex Cytosol	Nucleus Cytoplasm
	Molecular Function	Transcription Corepressor Activity Protein Binding	Molecular_function SH3 Domain Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Deacetylation Negative Regulation Of Transcription, DNA-templated	Homologous Chromosome Segregation Chromosome Organization Negative Regulation Of Mitotic Sister Chromatid Separation
Pathways
Drugs
Diseases
GWAS		Plateletcrit ( 32888494)	Metabolite levels ( 23823483) Periodontal microbiota ( 22699663) Response to antidepressants (symptom remission) ( 29160301) Response to SSRI (symptom remission) ( 29160301)
Interacting Genes		74 interacting genes: ABI1 ANKRD11 APP BHLHB9 BORCS6 CBY2 CCDC102B CCDC106 CCHCR1 CDR2 CEP55 CEP63 CEP70 EFHC2 FAM81A FSD2 GKAP1 GLRX3 GOLGA2 GRIPAP1 GSE1 HAUS3 HMBOX1 HOOK2 HSF2BP ICA1L IKZF3 ING5 ISY1-RAB43 KDM1A KRT15 KRT18 KRT19 KRT24 KRT27 KRT31 KRT40 KRT75 LCA5 LHX3 LUZP4 LZTS2 MAGEA6 MCC MESD MID2 MIPOL1 MTUS2 NDUFB7 NECAB2 NINL NRDE2 NUTM1 PHF19 PHF21B PIH1D1 PRDM14 PTTG2 STN1 SUMO2 TFIP11 TRAF1 TRAF2 TRIM27 TRIM42 TRIM54 TSGA10 TULP3 TXLNA USHBP1 VAX1 YWHAQ ZNF383 ZNF688	12 interacting genes: AGR2 APP CSNK2B EML2 PRR20A PRR20B PRR20C PRR20D PRR20E RCOR3 RIPPLY1 SUOX
Entrez ID		55758	10744
HPRD ID		08338	09176
Ensembl ID		ENSG00000117625	ENSG00000250254
Uniprot IDs		Q9P2K3	Q9NZH5
PDB IDs		4CZZ
Enriched GO Terms of Interacting Partners?
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