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LIME1 and TMBIM6
Data Source:
BioGRID
(two hybrid)
LIME1
TMBIM6
Description
Lck interacting transmembrane adaptor 1
transmembrane BAX inhibitor motif containing 6
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Integral Component Of Membrane
B Cell Receptor Complex
Nucleus
Cytoplasm
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Molecular Function
Protein Binding
Protein Kinase Binding
Protein Binding
Enzyme Binding
Ubiquitin Protein Ligase Binding
Endoribonuclease Inhibitor Activity
Biological Process
Adaptive Immune Response
Regulation Of Transcription By RNA Polymerase II
Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of MAP Kinase Activity
T Cell Receptor Signaling Pathway
B Cell Receptor Signaling Pathway
Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of Immunoglobulin Production
Autophagy
Negative Regulation Of Calcium Ion Transport Into Cytosol
Negative Regulation Of Protein Binding
Endoplasmic Reticulum Calcium Ion Homeostasis
Negative Regulation Of RNA Splicing
Cellular Response To Unfolded Protein
Negative Regulation Of Apoptotic Process
Negative Regulation Of Endoribonuclease Activity
Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Response To L-glutamate
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress
Negative Regulation Of Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Asthma (
31619474
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Crohn's disease (
28067908
)
Estimated glomerular filtration rate (
31015462
)
Inflammatory bowel disease (
28067908
23128233
)
Meat-related diet (
32066663
)
Prostate cancer (
23535732
)
Refractive error (
32231278
)
Ulcerative colitis (
28067908
)
General cognitive ability (
29844566
)
Interacting Genes
46 interacting genes:
AGR3
AIG1
AQP1
ARFGAP3
BNIP2
C14orf180
CALN1
CIAO2A
CLN6
EMD
FRMD8
GAD2
GOSR2
GRB2
LCK
LHFPL5
LPAR3
LYN
MAN2B2
MEST
MIEF2
NDRG4
NINJ1
PBX3
PKMYT1
PLCG2
PNPO
PTPN9
RTP2
SEC22C
SLC41A2
SNAP47
SNX1
STX6
STX7
TBRG4
TMBIM6
TMEM143
TMEM243
TMEM74
TMEM86B
TMEM97
TRAF3IP3
UNC93B1
UPK2
ZFPL1
68 interacting genes:
ADIPOR2
ATP13A1
BCL2
BCL2L1
CD300LG
CD79A
CD99L2
CDC7
CERS2
CLDN22
COBLL1
CREB3L1
EBP
ENPP4
ERP29
ESAM
FAM209A
FERD3L
FGFBP2
FXYD3
GJA5
GJA8
GJB4
GLP1R
GPHB5
GPR151
GPR42
GPX8
GYPA
GZMK
HERPUD2
HJV
HTR2C
IER3
JSRP1
KCNA10
KCNC1
LIME1
LRRC59
MANBAL
MFSD14B
MMGT1
MS4A3
ODF4
OPRM1
PI16
PIANP
PVR
REEP2
RHBDL2
RNF185
SCN3B
SIT1
SLAMF6
SLC12A7
SLC41A3
SLC7A1
SOAT2
STEAP1B
SYT9
TEX29
TMEM31
TMUB1
TMX2
TNFRSF17
TREML1
UGT2B11
VTI1A
Entrez ID
54923
7009
HPRD ID
07904
02851
Ensembl ID
ENSG00000203896
ENSG00000139644
Uniprot IDs
A0A087WT39
Q9H400
A0A024R0Z5
P55061
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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