LIME1 and ARFGAP3

Data Source:
BioGRID (two hybrid)

		LIME1	ARFGAP3
Description		Lck interacting transmembrane adaptor 1	ADP ribosylation factor GTPase activating protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane B Cell Receptor Complex	Golgi Membrane Golgi Apparatus Cytosol Membrane
	Molecular Function	Protein Binding Protein Kinase Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Adaptive Immune Response Regulation Of Transcription By RNA Polymerase II Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of MAP Kinase Activity T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of NIK/NF-kappaB Signaling	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Secretion Vesicle-mediated Transport Positive Regulation Of GTPase Activity COPI Coating Of Golgi Vesicle
Pathways			COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Crohn's disease ( 28067908) Estimated glomerular filtration rate ( 31015462) Inflammatory bowel disease ( 28067908 23128233) Meat-related diet ( 32066663) Prostate cancer ( 23535732) Refractive error ( 32231278) Ulcerative colitis ( 28067908)	Resting metabolic rate ( 28476931)
Interacting Genes		46 interacting genes: AGR3 AIG1 AQP1 ARFGAP3 BNIP2 C14orf180 CALN1 CIAO2A CLN6 EMD FRMD8 GAD2 GOSR2 GRB2 LCK LHFPL5 LPAR3 LYN MAN2B2 MEST MIEF2 NDRG4 NINJ1 PBX3 PKMYT1 PLCG2 PNPO PTPN9 RTP2 SEC22C SLC41A2 SNAP47 SNX1 STX6 STX7 TBRG4 TMBIM6 TMEM143 TMEM243 TMEM74 TMEM86B TMEM97 TRAF3IP3 UNC93B1 UPK2 ZFPL1	8 interacting genes: APP CD14 CXCL8 LIME1 RTN4IP1 SMAD2 SYPL1 ZDHHC17
Entrez ID		54923	26286
HPRD ID		07904	06444
Ensembl ID		ENSG00000203896	ENSG00000242247
Uniprot IDs		A0A087WT39 Q9H400	A0A024R4U0 Q9NP61
PDB IDs			2CRW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?