MIS18A and GCSH

Data Source:
BioGRID (two hybrid)

		MIS18A	GCSH
Description		MIS18 kinetochore protein A	glycine cleavage system protein H
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytosol	Cytoplasm Mitochondrion Mitochondrial Matrix Glycine Cleavage Complex
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Aminomethyltransferase Activity Protein Binding
	Biological Process	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of DNA Methylation Cell Division	Glycine Catabolic Process Protein Lipoylation Glycine Decarboxylation Via Glycine Cleavage System
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	Glyoxylate metabolism and glycine degradation Glycine degradation
Drugs			6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid Dihydrolipoic Acid
Diseases			Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
GWAS			Glycine levels ( 31070104 30837465) Metabolite levels (small molecules and protein measures) ( 27005778) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CCDC115 CNGA3 DMAP1 FNDC11 GCSH GLYCTK HJURP IFT20 MAFIP MBIP NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA ZNF471 ZNF655	10 interacting genes: CIDEB ING5 MAGEA11 MAGEA6 MED11 MIS18A NMI RHBDD2 SFI1 ZBTB16
Entrez ID		54069	2653
HPRD ID		10749	01998
Ensembl ID		ENSG00000159055	ENSG00000140905
Uniprot IDs		Q9NYP9	P23434
PDB IDs
Enriched GO Terms of Interacting Partners?
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