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GCSH and MAGEA11
Data Source:
BioGRID
(two hybrid)
GCSH
MAGEA11
Description
glycine cleavage system protein H
MAGE family member A11
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Glycine Cleavage Complex
Nucleoplasm
Cytosol
Nuclear Body
Molecular Function
Aminomethyltransferase Activity
Protein Binding
Protein Binding
Biological Process
Glycine Catabolic Process
Protein Lipoylation
Glycine Decarboxylation Via Glycine Cleavage System
Pathways
Glyoxylate metabolism and glycine degradation
Glycine degradation
Drugs
6-(Hydroxyethyldithio)-8-(Aminomethylthio)Octanoic Acid
Dihydrolipoic Acid
Diseases
Nonketotic hyperglycinemia; Glycine encephalopathy (GCE)
GWAS
Glycine levels (
31070104
30837465
)
Metabolite levels (small molecules and protein measures) (
27005778
)
Waist-to-hip ratio adjusted for BMI (age >50) (
26426971
)
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) (
26426971
)
Interacting Genes
10 interacting genes:
CIDEB
ING5
MAGEA11
MAGEA6
MED11
MIS18A
NMI
RHBDD2
SFI1
ZBTB16
114 interacting genes:
ACMSD
ACSM2B
ACTN1
AKR1C3
ALDH5A1
AR
ARHGAP29
BCL2L11
BEX2
BIRC2
BRD1
C18orf54
C22orf39
CASP7
CAVIN3
CCDC105
CCDC106
CCDC14
CCDC146
CCDC185
CCDC27
CCNA2
CDC20B
CDKN2B
CEP76
CLUAP1
CORO1A
COX7A2L
CSNK2A1
CTTNBP2
DLGAP1
DNAJC10
DOCK10
ENOX2
EWSR1
FAM156A
FAM161A
FBXO46
GADD45GIP1
GCSH
GNPDA1
HOXB5
IFI44
IL11
IL6ST
ILF3
JADE3
KIAA0408
LMBR1L
LNX1
MAPK3
MCRS1
MED28
MGME1
MLF1
MTA1
MXD3
MYOZ1
NCOA2
NDEL1
NDUFAF1
NDUFB9
NIF3L1
NOL4
NOS3
NSUN4
NTAQ1
OTUB2
PCBD2
PDE4B
PHYH
PIK3IP1
PIN4
PLCXD3
PNKD
PNKP
POLR1D
PPIF
PPM1K
PRDX3
PRKRIP1
PSMF1
RADIL
RANBP10
RBM23
REX1BD
SH2D4A
SNX20
SNX7
STAR
SUCLA2
SUOX
SUV39H2
TCEA2
TCEANC
TCF25
TEX37
THEM5
TMEM123
TPM3
TRIM27
TRIM51
TRMT1
TXN2
UBE2D4
UBE3D
USP20
UTP25
VTA1
WTAP
ZBTB16
ZCCHC12
ZNF655
ZSWIM2
Entrez ID
2653
4110
HPRD ID
01998
02281
Ensembl ID
ENSG00000140905
ENSG00000185247
Uniprot IDs
P23434
G5E962
P43364
PDB IDs
6WJH
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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