MIS18A and BRD8

Data Source:
BioGRID (two hybrid)

		MIS18A	BRD8
Description		MIS18 kinetochore protein A	bromodomain containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytosol	Swr1 Complex Nucleoplasm Mitochondrion NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding Nuclear Receptor Coactivator Activity Thyroid Hormone Receptor Binding
	Biological Process	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of DNA Methylation Cell Division	Cell Surface Receptor Signaling Pathway Histone Acetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Thyroid Hormone Stimulus
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	HATs acetylate histones
Drugs
Diseases
GWAS			Autism spectrum disorder or schizophrenia ( 28540026) Menarche (age at onset) ( 25231870)
Interacting Genes		30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CCDC115 CNGA3 DMAP1 FNDC11 GCSH GLYCTK HJURP IFT20 MAFIP MBIP NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA ZNF471 ZNF655	12 interacting genes: AGTR1 EP400 FSD2 MCRS1 MIS18A MRGBP PIN1 PPARG RXRA THRB TRRAP WEE1
Entrez ID		54069	10902
HPRD ID		10749	04166
Ensembl ID		ENSG00000159055	ENSG00000112983
Uniprot IDs		Q9NYP9	B4DEG9 B4DMS9 B4DN43 Q9H0E9
PDB IDs
Enriched GO Terms of Interacting Partners?
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