MIS18A and ATG14

Data Source:
BioGRID (two hybrid)

		MIS18A	ATG14
Description		MIS18 kinetochore protein A	autophagy related 14
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Cytosol	Autophagosome Membrane Autophagosome Endoplasmic Reticulum Membrane Cytosol Axoneme Phagophore Assembly Site Membrane Phosphatidylinositol 3-kinase Complex, Class III Mitochondria-associated Endoplasmic Reticulum Membrane Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding Identical Protein Binding Metal Ion Binding	Protein Binding GTPase Binding
	Biological Process	Cell Cycle Chromosome Segregation CENP-A Containing Nucleosome Assembly Regulation Of DNA Methylation Cell Division	Autophagosome Assembly Mitophagy Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Protein Phosphorylation Endosome To Lysosome Transport Cellular Response To Starvation Posttranscriptional Regulation Of Gene Expression Macroautophagy Autophagosome Membrane Docking Cellular Response To Glucose Starvation Positive Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Protein Complex Stability Regulation Of Triglyceride Metabolic Process Response To Mitochondrial Depolarisation
Pathways		Deposition of new CENPA-containing nucleosomes at the centromere	Macroautophagy
Drugs
Diseases
GWAS			Blood protein levels ( 28240269) Eosinophil percentage of white cells ( 32888494) Platelet distribution width ( 27863252) Statin-induced myopathy ( 31220337) Testicular germ cell tumor ( 28604728) White blood cell count ( 32888494)
Interacting Genes		30 interacting genes: ABI3 AIMP2 AMOT ATG14 BRD8 C1orf216 CCDC115 CNGA3 DMAP1 FNDC11 GCSH GLYCTK HJURP IFT20 MAFIP MBIP NDEL1 NTAQ1 NUP58 OIP5 PPP1R13B RTP5 STX11 STX17 TEDC2 THAP1 TSGA10IP TXLNA ZNF471 ZNF655	9 interacting genes: ATG13 EXOC1 FSD2 MIS18A RACK1 SNAPIN STX17 STYK1 ULK2
Entrez ID		54069	22863
HPRD ID		10749	13820
Ensembl ID		ENSG00000159055	ENSG00000126775
Uniprot IDs		Q9NYP9	Q6ZNE5
PDB IDs			6HOL
Enriched GO Terms of Interacting Partners?
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