ATP7B and DCTN4

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid, in vivo)

		ATP7B	DCTN4
Description		ATPase copper transporting beta	dynactin subunit 4
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrion Late Endosome Golgi Apparatus Trans-Golgi Network Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Kinetochore Spindle Pole Stress Fiber Nucleus Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Dynactin Complex Focal Adhesion Cell Cortex Sarcomere
	Molecular Function	Copper Ion Transmembrane Transporter Activity Copper Ion Binding Protein Binding ATP Binding P-type Divalent Copper Transporter Activity	Protein Binding Protein N-terminus Binding
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Copper Ion Import Ion Transmembrane Transport Response To Copper Ion Sequestering Of Calcium Ion Copper Ion Export Inorganic Cation Transmembrane Transport	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		Ion transport by P-type ATPases	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases		Wilson disease; Hepatolenticular degeneration
GWAS		Clostridium difficile infection in multiple myeloma ( 29594489) Mean spheric corpuscular volume ( 32888494) Waist circumference adjusted for body mass index ( 28552196)	Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma ( 28604730)
Interacting Genes		4 interacting genes: ATOX1 DCTN4 HP ZBTB16	8 interacting genes: ACTR10 ACTR1A ATP7B CALCOCO2 GOLGA2 HMG20A MTUS2 PNMA1
Entrez ID		540	51164
HPRD ID		06050	13126
Ensembl ID		ENSG00000123191	ENSG00000132912
Uniprot IDs		A0A024RDX3 A0A669KB88 B7ZLR3 B7ZLR4 E7ET55 P35670	A0A0S2Z5D4 Q9NSJ5 Q9UJW0
PDB IDs		2ARF 2EW9 2KOY 2LQB 2N7Y 2ROP 6A71 6A72
Enriched GO Terms of Interacting Partners?
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