DCTN4 and ACTR10

Data Source:
BioGRID (two hybrid)

		DCTN4	ACTR10
Description		dynactin subunit 4	actin related protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Spindle Pole Stress Fiber Nucleus Cytoplasm Centrosome Cytosol Cytoplasmic Dynein Complex Dynactin Complex Focal Adhesion Cell Cortex Sarcomere	Extracellular Region Cytosol Dynactin Complex Azurophil Granule Lumen Axon Cytoplasm Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Protein N-terminus Binding	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Neutrophil Degranulation Retrograde Axonal Transport Of Mitochondrion
Pathways		MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908) Lung adenocarcinoma ( 28604730)	Alcohol consumption ( 31358974) Brain morphology (MOSTest) ( 32665545) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		8 interacting genes: ACTR10 ACTR1A ATP7B CALCOCO2 GOLGA2 HMG20A MTUS2 PNMA1	7 interacting genes: ACTA1 DCTN4 HOMEZ KRT31 NAGK RXFP4 SLC13A1
Entrez ID		51164	55860
HPRD ID		13126	12420
Ensembl ID		ENSG00000132912	ENSG00000131966
Uniprot IDs		A0A0S2Z5D4 Q9NSJ5 Q9UJW0	Q86SY7 Q9NZ32
PDB IDs
Enriched GO Terms of Interacting Partners?
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