ATP7B and ATOX1

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		ATP7B	ATOX1
Description		ATPase copper transporting beta	antioxidant 1 copper chaperone
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GO Annotations	Cellular Component	Golgi Membrane Mitochondrion Late Endosome Golgi Apparatus Trans-Golgi Network Integral Component Of Plasma Membrane Membrane Basolateral Plasma Membrane Cytoplasmic Vesicle Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm	Cytosol
	Molecular Function	Copper Ion Transmembrane Transporter Activity Copper Ion Binding Protein Binding ATP Binding P-type Divalent Copper Transporter Activity	Copper Ion Binding Protein Binding Metallochaperone Activity Copper Chaperone Activity Copper-dependent Protein Binding
	Biological Process	Copper Ion Transport Cellular Copper Ion Homeostasis Copper Ion Import Ion Transmembrane Transport Response To Copper Ion Sequestering Of Calcium Ion Copper Ion Export Inorganic Cation Transmembrane Transport	Copper Ion Transport Cellular Copper Ion Homeostasis Response To Oxidative Stress
Pathways		Ion transport by P-type ATPases	Detoxification of Reactive Oxygen Species Ion influx/efflux at host-pathogen interface
Drugs			Cisplatin Sucrose Benzamidine
Diseases		Wilson disease; Hepatolenticular degeneration
GWAS		Clostridium difficile infection in multiple myeloma ( 29594489) Mean spheric corpuscular volume ( 32888494) Waist circumference adjusted for body mass index ( 28552196)	Creatinine levels ( 29403010) Glomerular filtration rate ( 29403010) Red cell distribution width ( 32888494) Systolic blood pressure change trajectories ( 27980656)
Interacting Genes		4 interacting genes: ATOX1 DCTN4 HP ZBTB16	8 interacting genes: ATP7A ATP7B CFAP410 COMP FAM118A FKBP4 GGPS1 NECAB1
Entrez ID		540	475
HPRD ID		06050	03779
Ensembl ID		ENSG00000123191	ENSG00000177556
Uniprot IDs		A0A024RDX3 A0A669KB88 B7ZLR3 B7ZLR4 E7ET55 P35670	O00244
PDB IDs		2ARF 2EW9 2KOY 2LQB 2N7Y 2ROP 6A71 6A72	1FE0 1FE4 1FEE 1TL4 1TL5 2K1R 2LQ9 3CJK 3IWL 3IWX 4QOT 4YDX 4YEA 5F0W 5T7L
Enriched GO Terms of Interacting Partners?
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