ATP6V1G2 and USP20

Data Source:
BioGRID (two hybrid)

		ATP6V1G2	USP20
Description		ATPase H+ transporting V1 subunit G2	ubiquitin specific peptidase 20
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Vacuolar Proton-transporting V-type ATPase Complex Melanosome	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding ATPase-coupled Transmembrane Transporter Activity	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein Phosphopantetheinylation Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Ub-specific processing proteases
Drugs		Tiludronic acid
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) LDL cholesterol levels ( 32203549) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Myositis ( 26291516) Ulcerative colitis ( 28067908)	Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: ATP6V1E1 ATP6V1E2 USP20	69 interacting genes: AGR2 ALAS1 APBA2 ARID5A ASCL1 ATP6V1G2 BEND5 BEND7 BHLHB9 BRPF1 C1QTNF2 CCNL2 CDK2AP1 CLSPN CTAG1A CTAG1B DIO2 ENKD1 EPAS1 FATE1 FTO GPRASP2 GTF2IRD1 HAND2 HIF1A HSF2BP IHO1 IRAK1BP1 ITGB3BP KLHL20 LMNA MAGEA11 MAPK6 MBD3L1 MCCD1 MDFI MEOX2 MRPL28 PBX4 PJA1 PLA2G2A PRKACA PRKCI RAD17 RSPO4 SAMD12 SPRY2 SRGAP2B STING1 TNNI1 TRIB3 TRIM23 TTC19 TTC23L ULK1 USP15 USP21 USP28 VAPA VAPB VAX1 VHL WASHC1 ZBTB10 ZFYVE26 ZNF343 ZNF408 ZNF620 ZXDB
Entrez ID		534	10868
HPRD ID		06030	07505
Ensembl ID		ENSG00000213760	ENSG00000136878
Uniprot IDs		O95670 Q6NVJ2	Q9Y2K6
PDB IDs			6KCZ
Enriched GO Terms of Interacting Partners?
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