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USP20 and CLSPN
Data Source:
BioGRID
(affinity chromatography technology, enzymatic study)
USP20
CLSPN
Description
ubiquitin specific peptidase 20
claspin
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Centrosome
Cytosol
Perinuclear Region Of Cytoplasm
Nucleus
Nucleoplasm
Golgi Apparatus
Molecular Function
G Protein-coupled Receptor Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Zinc Ion Binding
DNA Secondary Structure Binding
Protein Binding
Anaphase-promoting Complex Binding
Biological Process
Ubiquitin-dependent Protein Catabolic Process
Endocytosis
Regulation Of G Protein-coupled Receptor Signaling Pathway
Protein Deubiquitination
Protein Phosphopantetheinylation
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
DNA Replication Checkpoint
DNA Damage Checkpoint
DNA Replication
DNA Repair
Mitotic G2 DNA Damage Checkpoint
Protein Deubiquitination
Peptidyl-serine Phosphorylation
Activation Of Protein Kinase Activity
Mitotic DNA Replication Checkpoint
Pathways
Ub-specific processing proteases
Apoptotic cleavage of cellular proteins
Activation of ATR in response to replication stress
Ub-specific processing proteases
Processing of DNA double-strand break ends
Drugs
Diseases
GWAS
Metabolite levels (
23823483
)
Mean corpuscular hemoglobin (
32888494
)
Mean corpuscular volume (
32888494
)
Waist-to-hip ratio adjusted for BMI (additive genetic model) (
30778226
)
Interacting Genes
69 interacting genes:
AGR2
ALAS1
APBA2
ARID5A
ASCL1
ATP6V1G2
BEND5
BEND7
BHLHB9
BRPF1
C1QTNF2
CCNL2
CDK2AP1
CLSPN
CTAG1A
CTAG1B
DIO2
ENKD1
EPAS1
FATE1
FTO
GPRASP2
GTF2IRD1
HAND2
HIF1A
HSF2BP
IHO1
IRAK1BP1
ITGB3BP
KLHL20
LMNA
MAGEA11
MAPK6
MBD3L1
MCCD1
MDFI
MEOX2
MRPL28
PBX4
PJA1
PLA2G2A
PRKACA
PRKCI
RAD17
RSPO4
SAMD12
SPRY2
SRGAP2B
STING1
TNNI1
TRIB3
TRIM23
TTC19
TTC23L
ULK1
USP15
USP21
USP28
VAPA
VAPB
VAX1
VHL
WASHC1
ZBTB10
ZFYVE26
ZNF343
ZNF408
ZNF620
ZXDB
11 interacting genes:
ATR
BRCA1
CASP7
CDC7
CHEK1
FZR1
RAD9A
USP20
USP28
USP29
USP7
Entrez ID
10868
63967
HPRD ID
07505
09257
Ensembl ID
ENSG00000136878
ENSG00000092853
Uniprot IDs
Q9Y2K6
Q9HAW4
PDB IDs
6KCZ
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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