ATP6V1G2 and ATP6V1E1

Data Source:
HPRD (two hybrid)

		ATP6V1G2	ATP6V1E1
Description		ATPase H+ transporting V1 subunit G2	ATPase H+ transporting V1 subunit E1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Vacuolar Proton-transporting V-type ATPase Complex Melanosome	Lysosomal Membrane Endosome Cytosol Microvillus Apical Plasma Membrane Proton-transporting Two-sector ATPase Complex Proton-transporting Two-sector ATPase Complex, Catalytic Domain Extracellular Exosome
	Molecular Function	Protein Binding ATPase-coupled Transmembrane Transporter Activity	Protein Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Hydrolase Activity Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid	Tiludronic acid
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) LDL cholesterol levels ( 32203549) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Myositis ( 26291516) Ulcerative colitis ( 28067908)
Interacting Genes		3 interacting genes: ATP6V1E1 ATP6V1E2 USP20	14 interacting genes: ALDOA ALDOB ALDOC APP ATP6V0E1 ATP6V1G1 ATP6V1G2 ATP6V1H HSPB2 MESD SLC9A3R1 SOS1 TRAF6 XRCC6
Entrez ID		534	529
HPRD ID		06030	00163
Ensembl ID		ENSG00000213760	ENSG00000131100
Uniprot IDs		O95670 Q6NVJ2	P36543 Q53Y06
PDB IDs
Enriched GO Terms of Interacting Partners?
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