ATP6V1G2 and ATP6V1E2

Data Source:
BioGRID (two hybrid)

		ATP6V1G2	ATP6V1E2
Description		ATPase H+ transporting V1 subunit G2	ATPase H+ transporting V1 subunit E2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Vacuolar Proton-transporting V-type ATPase Complex Melanosome	Acrosomal Vesicle Cytosol Proton-transporting Two-sector ATPase Complex, Catalytic Domain
	Molecular Function	Protein Binding ATPase-coupled Transmembrane Transporter Activity	Protein Binding Proton-exporting ATPase Activity, Phosphorylative Mechanism Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport	Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid	Tiludronic acid
Diseases
GWAS		Asthma ( 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Inflammatory bowel disease ( 28067908) LDL cholesterol levels ( 32203549) Malaria ( 31844061) Monocyte percentage of white cells ( 32888494) Myositis ( 26291516) Ulcerative colitis ( 28067908)	Anti-saccade error rate in psychotic disorders ( 29064472) Anti-saccade response ( 29064472) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		3 interacting genes: ATP6V1E1 ATP6V1E2 USP20	5 interacting genes: ATP6V1G1 ATP6V1G2 BBLN MESD RASSF10
Entrez ID		534	90423
HPRD ID		06030	16525
Ensembl ID		ENSG00000213760	ENSG00000250565
Uniprot IDs		O95670 Q6NVJ2	A0A140VKA8 Q96A05
PDB IDs
Enriched GO Terms of Interacting Partners?
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