PLD2 and TIMM10B

Data Source:
BioGRID (affinity chromatography technology)

		PLD2	TIMM10B
Description		phospholipase D2	translocase of inner mitochondrial membrane 10B
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Presynapse	Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Mitochondrial Intermembrane Space Protein Transporter Complex TIM22 Mitochondrial Import Inner Membrane Insertion Complex
	Molecular Function	Phospholipase D Activity Protein Binding Phosphatidylinositol Binding N-acylphosphatidylethanolamine-specific Phospholipase D Activity	Protein Binding Metal Ion Binding Protein Transporter Activity
	Biological Process	Phosphatidic Acid Biosynthetic Process Cytoskeleton Organization Small GTPase Mediated Signal Transduction Lipid Catabolic Process Synaptic Vesicle Recycling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Inositol Lipid-mediated Signaling Cell Motility	Protein Targeting To Mitochondrion Cell-matrix Adhesion Protein Insertion Into Mitochondrial Inner Membrane
Pathways		Synthesis of PG Synthesis of PA Role of phospholipids in phagocytosis	Mitochondrial protein import
Drugs		Choline Choline salicylate
Diseases
GWAS		Sphingolipid levels ( 22359512) Systemic lupus erythematosus ( 26502338)	Malaria ( 31844061)
Interacting Genes		29 interacting genes: ACTB ACTN1 ALDOA ALDOC AMPH AQP3 ARF1 BIN1 CAV1 CSK DPYSL2 EGFR FYN GAPDH GM2A HIF1A LCK MTDH MTOR OPRM1 PEA15 PIP5K1A PLCG1 PRKCA PRKCD RPTOR SRC STXBP1 VHL	5 interacting genes: EIF3F HGS KLHL38 MBD3 MEIS2
Entrez ID		5338	26515
HPRD ID		03857	16242
Ensembl ID		ENSG00000129219	ENSG00000132286
Uniprot IDs		O14939	B2R4A9 Q9Y5J6
PDB IDs		6OHM 6OHO 6OHP 6OHQ 6OHS	7CGP
Enriched GO Terms of Interacting Partners?
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