PDZK1 and AKAP10

Data Source:
HPRD (two hybrid, in vitro)

		PDZK1	AKAP10
Description		PDZ domain containing 1	A-kinase anchoring protein 10
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GO Annotations	Cellular Component	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome	Mitochondrion Cytosol Plasma Membrane Protein-containing Complex
	Molecular Function	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding	Protein Binding Protein Kinase A Binding
	Biological Process	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Signal Transduction Blood Coagulation Protein Localization
Pathways			Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Contrast sensitivity ( 24152035) Gout ( 32238385) Serum uric acid levels ( 30993211) Urate levels ( 31985003 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)	Body mass index ( 29273807) Brain morphology (MOSTest) ( 32665545) Hemoglobin levels ( 32327693) Mean platelet volume ( 27863252) Neutrophil count ( 32888494) Platelet count ( 22139419 32888494 27863252) Schizophrenia ( 28991256) Strenuous sports or other exercises ( 29899525)
Interacting Genes		31 interacting genes: ABCA1 ABCC2 ABCC4 ACE2 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC13A1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	7 interacting genes: IKZF3 PDZK1 PRKAR1A PRKAR2A PRKAR2B SASH1 SLC9A3R1
Entrez ID		5174	11216
HPRD ID		04829	05259
Ensembl ID		ENSG00000174827	ENSG00000108599
Uniprot IDs		Q5T2W1	A0A0S2Z4Z7 E7EMD6 O43572
PDB IDs		2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI	3IM4 3TMH
Enriched GO Terms of Interacting Partners?
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