PDZK1 and SLC17A1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro)

		PDZK1	SLC17A1
Description		PDZ domain containing 1	solute carrier family 17 member 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome	Lysosome Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Apical Plasma Membrane
	Molecular Function	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding	Sodium:phosphate Symporter Activity Phosphate Ion Transmembrane Transporter Activity Sialic Acid Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	Ion Transport Phosphate Ion Transport Anion Transport Sialic Acid Transport Urate Transport Phosphate Ion Transmembrane Transport Sodium Ion Transmembrane Transport Urate Metabolic Process
Pathways			Organic anion transporters
Drugs
Diseases
GWAS		Contrast sensitivity ( 24152035) Gout ( 32238385) Serum uric acid levels ( 30993211) Urate levels ( 31985003 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)	Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) General cognitive ability ( 29844566) Gout ( 32238385 27899376) Intelligence (MTAG) ( 29326435) Iron status biomarkers ( 21208937 19084217) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Red blood cell traits ( 20927387) Refractive error ( 32231278) Schizophrenia ( 19571809) Serum uric acid levels ( 30993211 29403010) Subcortical volume (MOSTest) ( 32665545) Tenofovir clearance in HIV infection ( 26148204) Urate levels ( 31985003 20884846 31578528 23263486) Urate levels in lean individuals ( 25811787) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
Interacting Genes		31 interacting genes: ABCA1 ABCC2 ABCC4 ACE2 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC13A1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	1 interacting genes: PDZK1
Entrez ID		5174	6568
HPRD ID		04829	01661
Ensembl ID		ENSG00000174827	ENSG00000124568
Uniprot IDs		Q5T2W1	Q14916
PDB IDs		2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI
Enriched GO Terms of Interacting Partners?
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