PDZK1 and SSTR5

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		PDZK1	SSTR5
Description		PDZ domain containing 1	somatostatin receptor 5
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Brush Border Apical Plasma Membrane Brush Border Membrane Microvillus Membrane Membrane Raft Extracellular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Scavenger Receptor Binding Protein Binding PDZ Domain Binding Protein-membrane Adaptor Activity Protein-containing Complex Binding	G Protein-coupled Receptor Activity Somatostatin Receptor Activity Peptide Binding Neuropeptide Binding
	Biological Process	Carnitine Transport Positive Regulation Of Ion Transmembrane Transporter Activity Regulation Of Anion Transport Protein Localization To Plasma Membrane Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Cation Transmembrane Transport Positive Regulation Of Protein Localization To Membrane Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cytokinesis Somatostatin Signaling Pathway Glucose Homeostasis Regulation Of Insulin Secretion Cellular Response To Glucocorticoid Stimulus
Pathways			Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Vapreotide Pasireotide Lanreotide Somatostatin Lutetium Lu 177 dotatate Edotreotide gallium Ga-68
Diseases
GWAS		Contrast sensitivity ( 24152035) Gout ( 32238385) Serum uric acid levels ( 30993211) Urate levels ( 31985003 20884846 31578528 23263486) Urate levels in overweight individuals ( 25811787) Uric acid levels ( 19503597)	Logical memory (immediate recall) in normal cognition ( 29274321) Polycystic ovary syndrome ( 25574032)
Interacting Genes		31 interacting genes: ABCA1 ABCC2 ABCC4 ACE2 AKAP10 APP CFTR CLCN3 CRHR1 FARP2 GFAP PDZK1IP1 PEX5 RPS6KA1 SCARB1 SLC13A1 SLC15A2 SLC17A1 SLC22A11 SLC22A12 SLC22A4 SLC22A5 SLC26A6 SLC34A1 SLC9A3 SLC9A3R1 SLC9A3R2 SLCO1A2 SLK SSTR5 UBE2I	9 interacting genes: ADCY10 CNR1 CORT DRD2 GOPC PDZK1 PEX5 SST SSTR1
Entrez ID		5174	6755
HPRD ID		04829	01677
Ensembl ID		ENSG00000174827	ENSG00000162009
Uniprot IDs		Q5T2W1	P35346
PDB IDs		2EEI 2EEJ 2VSP 3TMH 4Q2P 6EZI
Enriched GO Terms of Interacting Partners?
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